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fluvastatin
SynDRA canonical compound SYN0041638 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CYP2C8 | HMGCR |
|---|
| Mechanism of action | HMGCR inhibitor |
|---|
| Indication | congenital heart defects | hypercholesterolemia |
|---|
| Disease area | cardiology | endocrinology |
|---|
All known targets
- HMGCR
- CYP2C8
- CYP2C9
- Hmgcr
- NR1I3
- NR4A2
- RXRA
- SIRT6
- SLC10A1
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- APOBEC3G
- SAMHD1
- USP2
- USP1
- TP53
- TDP1
- TARDBP
- SMAD3
- NR2E3
- CGA
- NFE2L2
- IDH1
- GMNN
- GLP1R
- EYA2
- EHMT2
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ALR
- BARD1
- BRCA1
- EPAS1
- IDHC
- KSYK
- MDM2
- MDM4
- NSD2
- SYK
Drug classes
- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- HMG-CoA Reductase Inhibitor
ATC classes
- LIPID MODIFYING AGENTS, PLAIN
Cross-references
Synonyms
- lescol
- leschol
- fluvastatin sodium
- XU-62-320
- fluvastatin sodium salt
- fluvastatin sodium hydrate
- 4L066368AS
- Fluvas
- NSC 758896
- Fluvastatine
- Fluvastatina
- Fluvastatinum
- CHEBI:5136
- XU 62320
- CHEBI:38561
- DTXCID0065309
- RefChem:56568
- C10AA04
- Fluvastatine [INN-French]
- Fluvastatinum [INN-Latin]
- Fluvastatina [INN-Spanish]
- (3S,5R)-fluvastatin
- (-)-3s,5r-fluvastatin sodium salt
- Fluvastatin (INN)
- FLUVASTATIN [INN]
- Fluvastatin [INN:BAN]
- UNII-4L066368AS
- (+-)-fluvastatin
- Fluvas (TN)
- Fluvastatin Impurity 13
- FLUVASTATIN [MI]
- Prestwick3_000859
- FLUVASTATIN [VANDF]
- rac-(3R,5S)-fluvastatin
- SCHEMBL2847
- BSPBio_000877
- FLUVASTATIN [WHO-DD]
- BIDD:GT0839
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