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ibuprofen guaiacol ester
SynDRA canonical compound SYN0041505 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PTGS2 |
|---|
| Mechanism of action | Cyclooxygenase inhibitor |
|---|
All known targets
- PTGS1
- PTGS2
- ASIC1
- SLC36A1
- SLC5A8
- CYP2C8
- CXCR1
- CXCR2
- CXCL8
- CYP2C9
- AKR1C2
- AKR1C3
Mechanisms of action (all sources)
- Cyclooxygenase inhibitor
- PTGS2 INHIBITOR
- PTGS1 INHIBITOR
- ASIC1 MODULATOR
- SLC36A1 INHIBITOR
- SLC5A8 INHIBITOR
- CXCR1 INHIBITOR
- CXCR2 INHIBITOR
- CXCL8 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
Drug classes
- Cyclooxygenase Inhibitors
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Inflammatory Agents
- Anti-Inflammatory Agents, Non-Steroidal
- Antirheumatic Agents
- Central Nervous System Agents
- Enzyme Inhibitors
- Peripheral Nervous System Agents
- Sensory System Agents
- Nonsteroidal Anti-inflammatory Drug
ATC classes
- G02C · OTHER GYNECOLOGICALS
- M01A · ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
- M02A · TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
- R02A · THROAT PREPARATIONS
- C01E · OTHER CARDIAC PREPARATIONS
- OPIOIDS
Cross-references
Synonyms
- methoxybutropate
- metoxibutropate
- Metoxibutropate
- Flubenil
- Methoxybutropate
- 2-Methoxyphenyl 2-(4-isobutylphenyl)propionate
- Guaiacol 4-isobutylhydratropate
- AF 2259
- 0N623MNK8Z
- AF 2259; Methoxybutropate; Metoxibutropate
- Benzeneacetic acid, alpha-methyl-4-(2-methylpropyl)-, 2-methoxyphenyl ester
- 2-METHOXYPHENYL 2-[4-(2-METHYLPROPYL)PHENYL]PROPANOATE
- EINECS 266-318-9
- BRN 2664678
- UNII-0N623MNK8Z
- Benflogin
- Benflogin (TN)
- 2-Methoxyphenyl alpha-methyl-4-(isobutyl)phenylacetate
- 2-(p-Isobutylphenyl)propionic acid o-methoxyphenyl ester
- alpha-Methyl-4-(2-methylpropyl)benzeneacetic acid 2-methoxyphenyl ester
- SCHEMBL5080304
- CHEMBL4795894
- (2-methoxyphenyl) 2-[4-(2-methylpropyl)phenyl]propanoate
- DTXSID10984948
- CHEBI:135336
- Propionic acid, 2-(p-isobutylphenyl)-, o-methoxyphenyl ester
- IBUPROFEN GUAIACOL ESTER [WHO-DD]
- 2-methoxyphenyl2-(4-isobutylphenyl)propanoate
- 2-methoxyphenyl 2-(4-isobutylphenyl)propanoate
- D08213
- EN300-18567259
- Q27236986
- Z3244866822
- guaiacol ibuprofen ester
- RefChem:910020
- orb1696117
- FVRWRGBTEHAPDI-UHFFFAOYSA-N
- EBC-50087
Reported adverse events
- Bleeding
- GI bleed
- Ulceration
- Perforation
- Elderly
- Addiction
- NGS
- Nausea
- Rash
- Depression
- Dizziness
- Dry eye
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