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AMG-319
SynDRA canonical compound SYN0039858 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | PIK3CD |
|---|
| Mechanism of action | PI3K inhibitor |
|---|
All known targets
- PIK3CD
- PIK3CA
- PIK3CB
- PIK3CG
Mechanisms of action (all sources)
- PIK3CD INHIBITOR
- PI3-kinase p110-delta subunit inhibitor
- PIK3CA INHIBITOR
- PIK3CB INHIBITOR
- PIK3CG INHIBITOR
- PI3K inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PIK3CB
- PIK3CG
- CYP2D6
- CYP3A4
- HDAC6
- NR1I2
- PIK3CA
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- AMG319
- J3.391.906I
- AMG 319
- RefChem:1050797
- MFCD28902228
- UNII-19DG7G1U5Q
- ACP319
- C21H16FN7
- 4wwn
- ACP-319
- GTPL8917
- orb1300494
- SCHEMBL4185718
- SCHEMBL28566037
- SCHEMBL29360036
- SCHEMBL29479154
- GLXC-90486
- AMG-319?
- EX-A1028
- AMG319 (ACP-319)
- NSC787137
- s7813
- AKOS025404931
- CCG-268471
- CS-5266
- NSC-787137
- NCGC00481653-02
- AC-35300
- AS-35220
- FA137646
- HY-12948
- T6757
- BRD-K21077415-001-01-5
- Z3064248238
- 3VC
- SCHEMBL16799298
- SCHEMBL29163616
- BRD-A58947127-001-01-6
Look up AMG-319 in the interactive SynDRA portal →