GSK-356278

SynDRA canonical compound SYN0039540 — structure-anchored drug synonym record

Clinical phase	Preclinical
Primary target(s)	PDE4A \| PDE4B \| PDE4C \| PDE4D
Mechanism of action	phosphodiesterase inhibitor

All known targets

PDE4A
PDE4B
PDE4D
PDE4C

Mechanisms of action (all sources)

phosphodiesterase inhibitor
PDE4D INHIBITOR
PDE4B INHIBITOR
PDE4A INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

PDE7A
ABL1
AURKA
BRD4
BRPF1
CDK2
CSNK1D
FGFR2
GSK3B
MAPK1
TRIM24

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

PDE3A
PDE3B

Cross-references

PubChem CID: 10252640
ChEMBL: CHEMBL4297384
DrugBank: DB12542
TTD: D0K9DI

Synonyms

GSK356278
GSK356278B
PDE4 inhibitor (oral, depression/anxiety), GlaxoSmithKline
1QTA9P992C
RefChem:144522
DTXCID00144892
MFCD27987927
UNII-1QTA9P992C
orb1305078
SCHEMBL2412775
SCHEMBL29392139
C21H25N7O2S
GLXC-04811
EX-A11252
AKOS027338707
SB16753
DA-38123
MS-27895
HY-106003
CS-0024611
NS00072268
T27475

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