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DORDAVIPRONE
SynDRA canonical compound SYN0039482 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | TNFRSF10A | TNFSF10 |
|---|
| Mechanism of action | AKT inhibitor | MAP kinase inhibitor |
|---|
All known targets
- AKT1
- CLPP
- DRD2
- DRD3
- MAPK1
- TNFRSF10A
- TNFSF10
Mechanisms of action (all sources)
- CLPP ACTIVATOR
- AKT1 INHIBITOR
- MEK inhibitor
- TNFSF10 MODULATOR
- DRD3 ANTAGONIST
- DRD2 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CYP2D6
- KCNH2
- CYP1A2
- CYP2B6
- CYP2C19
- CYP2C8
- CYP2C9
- CYP3A4
- GNA11
- GPR132
- HDAC6
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP2D6
- CP3A7
- KSYK
- NSD2
- SYK
Cross-references
Synonyms
- MODEYSO
- Modeyso
- Dordaviprona
- Onc-201
- ONC201
- NSC-350625
- TIC-10
- TIC10
- ONC 201
- UNII-9U35A31JAI
- 9U35A31JAI
- TIC10(ONC-201)
- TIC 10 active isomer
- ONC201(TIC10 isomer)
- TIC 10
- GTPL9978
- SCHEMBL16227974
- EX-A669
- AOB2892
- MolPort-039-137-731
- HY-15615A
- 3388AH
- s7963
- ZINC169620396
- AKOS025404904
- NSC 350625
- CS-3564
- AS-16735
- AK174891
- KB-335104
- FT-0700231
- J-690224
- ONC-201
- MFCD28118993
- Active isomer 2
- TIC10 compound
- Angular TIC10
- dordaviprone [INN]
- TIC10 active isomer
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