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A-485
SynDRA canonical compound SYN0039354 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | CREBBP | EP300 |
|---|
| Mechanism of action | histone acetyltransferase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- histone acetyltransferase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SLC6A3
- HTR2B
- TMEM97
- SLC6A4
- GABRA1
- PLK3
- PAK6
- PAK5
- PAK4
- OPRM1
- PDGFRA
- PDGFRB
- PAK3
- PAK2
- PAK1
- PDPK1
- PGR
- OXSR1
- AAK1
- OPRK1
- OPRD1
- OGG1
- NUAK2
- NUAK1
- NTRK3
- NTRK2
- NTRK1
- NTHL1
- NR3C1
- NLK
- NIM1K
- PHKA2
- PHKG1
- NEK7
- PI4KB
- PRKAA2
- PRKAA1
- PRCP
- PPIP5K1
- PPARG
Cross-references
Synonyms
- A 485
- A_485
- RefChem:1075125
- MFCD31619258
- A485
- C25H24F4N4O5
- orb1308704
- SCHEMBL17606148
- SCHEMBL29711903
- CHEBI:233363
- VRVJKILQRBSEAG-LFPIHBKWSA-N
- GLXC-10987
- EX-A3090
- BDBM50467836
- NSC842816
- NSC851765
- ZB1572
- AKOS034834101
- CS-8185
- NSC-842816
- NSC-851765
- NCGC00532330-04
- AC-36323
- BA166476
- BS-16194
- DA-60642
- SY334083
- HY-107455
- A-485?
- C91124
- T14073
- A-485; A 485; A485
- F546272
- 6TF
- N-[(4-fluorophenyl)methyl]-2-[(3R)-6-(methylcarbamoylamino)-2',4'-dioxospiro[1,2-dihydroindene-3,5'-1,3-oxazolidine]-3'-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]acetamide
- SCHEMBL17605954
- VRVJKILQRBSEAG-LNYMIDHXSA-N
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