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AZD2461

SynDRA canonical compound SYN0039283 — structure-anchored drug synonym record

Mechanisms of action (all sources)

• PARP inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• PARP1
• PRAP1
• ABL1
• AURKA
• BRD4
• BRPF1
• CDK2
• CSNK1D
• FGFR2
• GSK3B
• HDAC6
• MAPK1
• TRIM24

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• CP2C9
• CP3A7
• KSYK
• NSD2
• SYK

Cross-references

• PubChem CID: 44199317
• ChEMBL: CHEMBL4098253
• TTD: D07OIO
• LINCS BRD: BRD-K85014146

Synonyms

• AZD 2461
• UNII-3K288XF5XJ
• 3K288XF5XJ
• 4-(4-fluoro-3-(4-methoxypiperidine-1-carbonyl)benzyl)phthalazin-1(2H)-one
• 4-[4-Fluoro-3-[(4-methoxypiperidin-1-yl)carbonyl]benzyl]phthalazin-1(2H)-one
• 1(2H)-Phthalazinone, 4-[[4-fluoro-3-[(4-methoxy-1-piperidinyl)carbonyl]phenyl]methyl]-
• 4-(4-Fluoro-3-((4-methoxypiperidin-1-yl)carbonyl)benzyl)phthalazin-1(2H)-one
• 1(2H)-Phthalazinone, 4-((4-fluoro-3-((4-methoxy-1-piperidinyl)carbonyl)phenyl)methyl)-
• HYNBNUYQTQIHJK-UHFFFAOYSA-N
• SCHEMBL77012
• AZD-2461
• CHEMBL4098253
• AZD 2461 [WHO-DD]
• 4-[[4-fluoro-3-(4-methoxypiperidine-1-carbonyl)phenyl]methyl]-2H-phthalazin-1-one
• GTPL8472
• DTXSID00657831
• EX-A641
• HMS3652N16
• BCP07111
• BDBM50288530
• MFCD24386811
• NSC773230
• s7029
• ZINC95616578
• AKOS026750508
• AM81230
• CCG-264707
• CS-1402
• NSC-773230
• NCGC00381558-01
• NCGC00381558-03
• NCGC00381558-06
• AC-36007
• AS-55917
• HY-13536
• AZD2461, >=98% (HPLC)
• SW219802-1
• J-690044