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FGFR INHIBITOR DEBIO 1347
SynDRA canonical compound SYN0038626 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | FGFR1 | FGFR2 | FGFR3 |
|---|
| Mechanism of action | fibroblast growth factor inhibitor |
|---|
All known targets
- FGFR1
- FGFR2
- FGFR3
- FGFR4
- PDGFRB
Mechanisms of action (all sources)
- FGFR2 INHIBITOR
- Fibroblast growth factor receptor 2 inhibitor
- FGFR3 INHIBITOR
- Fibroblast growth factor receptor 3 inhibitor
- FGFR1 INHIBITOR
- Fibroblast growth factor receptor 1 inhibitor
- FGFR4 INHIBITOR
- PDGFRB INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SRC
- MAPKAPK2
- HDAC6
- PDXK
- SYK
- KCNH2
- KDR
- EPHB6
- RET
- ABL1
- PLK4
- PKN2
- PRKAR2A
- NQO2
- NTRK1
- NUAK2
- OLA1
- OPA1
- PAICS
- PAK2
- PAK4
- PEBP1
- PRKAG2
- PFKP
- PGRMC1
- PRKAG1
- PRKACB
- PHKG2
- NEK9
- PIM1
- PIM2
- PRKACA
- PRKAA1
- PIP4K2C
- PKMYT1
- PKN1
- NLK
- AAK1
- NEK3
- MARK3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP2D6
- CP3A7
- KSYK
- NR1I3
- NSD2
- PGFRB
Cross-references
Synonyms
- Zoligratinib
- Debio 1347
- CH5183284
- CH 5183284
- NR9ZYH80Z8
- FF284
- DEBIO1347
- Debiopharm 1347
- RefChem:196223
- debio 1347-101
- CH5183284 (Debio-1347)
- UNII-NR9ZYH80Z8
- BEMNJULZEQTDJY-UHFFFAOYSA-N
- MFCD28502053
- ZOLIGRATINIB [INN]
- ZOLIGRATINIB [WHO-DD]
- GTPL9787
- orb1301141
- SCHEMBL10002991
- SCHEMBL10313737
- SCHEMBL29358788
- SCHEMBL29434993
- GLXC-07218
- HMS3674G21
- HMS3748K13
- EX-A1122
- QAC22925
- BDBM50197683
- NSC782363
- NSC800074
- s7665
- AKOS027427006
- CH5183284; Debio-1347
- CCG-264725
- CS-5504
- EBC-220075
- NSC-782363
- NSC-800074
- SB16908
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