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VORUCICLIB
SynDRA canonical compound SYN0038624 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | CCND1 | CCNE1 | CCNT1 | CDK1 | CDK2 | CDK4 | CDK9 |
|---|
| Mechanism of action | CDK9 inhibitor |
|---|
All known targets
- CDK4
- CDK1
- CDK2
- CDK9
- CCND1
- DYRK1B
- MAP2K2
- LIMK1
- GSK3B
- GSK3A
- CDK8
- CSNK1G1
Mechanisms of action (all sources)
- CDK4/6 inhibitor
- Cyclin-dependent kinase 4 inhibitor
- CSNK1G1 INHIBITOR
- CDK1 INHIBITOR
- CDK2 INHIBITOR
- CDK5 INHIBITOR
- CDK8 INHIBITOR
- CDK9 INHIBITOR
- DYRK1B INHIBITOR
- GSK3A INHIBITOR
- GSK3B INHIBITOR
- LIMK1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CCNB1
- CCNT2
- DYR1B
- GSK3A
- GSK3B
- IFNB1
- KC1G1
- KSYK
- LIMK1
- NSD2
- PIM1
- SYK
Drug classes
- Antineoplastic Agents
- Protein Kinase Inhibitors
Cross-references
Synonyms
- P1446a-05
- P-1446
- P1446A-05
- W66XP666AM
- voruciclibum
- RefChem:902057
- Voruciclib [INN]
- UNII-W66XP666AM
- Voruciclib?
- MFCD28386202
- VORUCICLIB [WHO-DD]
- GTPL9923
- orb1310062
- SCHEMBL3108205
- SCHEMBL29366894
- SCHEMBL29788352
- MRPGRAKIAJJGMM-OCCSQVGLSA-N
- EX-A1056
- BDBM50193104
- NSC784284
- P1446A
- AKOS032946185
- NSC-784284
- T10096L
- NCGC00387877-01
- AC-31553
- AS-82346
- BP-40078
- DA-59047
- HY-12422
- CS-0011273
- F811928
- V582705
- rel-(2S,3R)-Voruciclib hydrochloride
- orb1708250
- 8BEP29W01U
- SCHEMBL29396331
- AKOS040740538
Look up VORUCICLIB in the interactive SynDRA portal →