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BMS-986142
SynDRA canonical compound SYN0038622 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | BTK |
|---|
| Mechanism of action | Bruton's tyrosine kinase (BTK) inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- BTK INHIBITOR
- Tyrosine-protein kinase BTK inhibitor
- Bruton's tyrosine kinase (BTK) inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- TXK
- BLK
- BMX
- TEC
- CD69
- SRC
- LCK
- KCNH2
- CYP2C8
- ITK
- CYP3A4
- FGFR3
- TRIM24
- MAPK1
- JAK2
- GSK3B
- ABL1
- CYP2D6
- AURKA
- CYP2C19
- CYP2B6
- CYP1A2
- CSNK1D
- CDK2
- BRPF1
- BRD4
- CYP2C9
Cross-references
Synonyms
- Unii-pjx9GH268R
- PJX9GH268R
- CHEMBL3900554
- GTPL9857
- SCHEMBL16319712
- BMS986142
- BDBM50194720
- AKOS032954006
- compound 14f [PMID: 27583770]
- J3.563.199B
- 73T
- 6-Fluoro-5-(R)-(3-(S)-(8-Fluoro-1-Methyl-2,4-Dioxo-1,2-Dihydroquinazolin-3(4h)-Yl)-2-Methylphenyl)-2-(S)-(2-Hydroxypropan-2-Yl)-2,3,4,9-Tetrahydro-1h-Carbazole-8-Carboxamide
- (7S)-3-fluoro-4-[3-(8-fluoro-1-methyl-2,4-dioxoquinazolin-3-yl)-2-methylphenyl]-7-(2-hydroxypropan-2-yl)-6,7,8,9-tetrahydro-5H-carbazole-1-carboxamide
- UNII-PJX9GH268R
- compound 14f (PMID: 27583770)
- RefChem:120770
- C32H30F2N4O4
- orb1302058
- SCHEMBL29564549
- SCHEMBL29564633
- SCHEMBL29564784
- GLXC-10581
- EX-A2778
- BMS986942
- NSC828251
- s8381
- ZB1608
- BMS 986142 [WHO-DD]
- AT14636
- NSC-828251
- BMS-986142?
- NCGC00846315-02
- BB170197
- MS-30322
- HY-101856
- CS-0022067
- SCHEMBL16319713
- AC-35810
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