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OLMUTINIB
SynDRA canonical compound SYN0038551 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | BTK | EGFR | ITK | JAK3 |
|---|
| Mechanism of action | Bruton's tyrosine kinase (BTK) inhibitor | EGFR inhibitor |
|---|
| Indication | non-small cell lung cancer (NSCLC) |
|---|
| Disease area | oncology |
|---|
All known targets
Mechanisms of action (all sources)
- EGFR INHIBITOR
- Epidermal growth factor receptor erbB1 inhibitor
- Bruton's tyrosine kinase (BTK) inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- TBXA2R
- DRD3
- PDE4A
- KDR
- KCNH2
- HTR1A
- HRH3
- OPRM1
- SLC6A3
- DRD1
- CHRM2
- CHRM1
- ADRA2A
- ADRA1A
- ADORA3
- SLC6A2
- PTGS1
- SLC6A4
- PGR
- PDE3A
- ABCB11
- MTOR
- MET
- MAOA
- ACHE
- HDAC6
- F2
- ESR1
- AR
- HTR2B
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
ATC classes
- L01E · PROTEIN KINASE INHIBITORS
Cross-references
Synonyms
- olita
- BI 1482694
- HM 61713
- olmutinib hydrochloride
- olmutinib HCl
- HM-61713
- BI-1482694
- HM61713
- CHL9B67L95
- olmutinibum
- RefChem:856756
- L01XE40
- DTXCID401748550
- MFCD29918158
- Olmutinib [INN]
- Olmutinib [WHO-DD]
- HM71224;Olmutinib
- Olmutinib (USAN/INN)
- Olmutinib [USAN:INN]
- OLMUTINIB [USAN]
- MG degrader compound E14
- Olmutinib(HM-71224)
- UNII-CHL9B67L95
- GTPL9196
- orb1298916
- orb1300347
- SCHEMBL14914931
- SCHEMBL29358219
- SCHEMBL29377940
- C26H26N6O2S
- EX-A879
- FDMQDKQUTRLUBU-UHFFFAOYSA-N
- GLXC-90435
- HMS5086K09
- BDBM50160871
- NSC792848
- NSC800980
- s8294
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