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AZD-3759
SynDRA canonical compound SYN0038349 — structure-anchored drug synonym record
| Clinical phase | Phase 2/Phase 3 |
|---|
| Primary target(s) | EGFR |
|---|
| Mechanism of action | EGFR inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- EGFR INHIBITOR
- Epidermal growth factor receptor erbB1 inhibitor
- KCNH2 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SRC
- KDR
- DRD2
- CYP1A2
- FLT1
- LYN
- LCK
- HDAC6
- FYN
- EPHB4
- CYP2B6
- CYP3A5
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C8
- CYP2C19
- YES1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- Zorifertinib
- AZD3759
- AZD 3759
- RefChem:115995
- MFCD29058564
- UNII-67SX9H68W2
- C22H23ClFN5O3
- A1CEL
- ZORIFERTINIB [INN]
- ZORIFERTINIB [WHO-DD]
- orb1303946
- SCHEMBL16010006
- SCHEMBL29483200
- SCHEMBL29837158
- SCHEMBL29996461
- GTPL10456
- EX-A720
- GLXC-90388
- BDBM50123453
- NSC788121
- NSC800978
- s7971
- AKOS027327321
- CCG-269329
- CS-5029
- EBC-157199
- NSC-788121
- NSC-800978
- compound 1m [PMID: 26313252]
- NCGC00483922-01
- NCGC00483922-02
- AC-29957
- AS-74755
- FA137650
- HY-18750
- T3659
- BRD-K41626799-001-01-1
- Z2471604138
- zorifertinib
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