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BMS-690514
SynDRA canonical compound SYN0038294 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | EGFR | ERBB2 | ERBB4 | FLT1 | FLT3 | FLT4 | KDR |
|---|
| Mechanism of action | EGFR inhibitor | VEGFR inhibitor |
|---|
All known targets
- EGFR
- ERBB2
- KDR
- ERBB4
- FLT1
- FLT3
- FLT4
Mechanisms of action (all sources)
- ERBB2 INHIBITOR
- Receptor protein-tyrosine kinase erbB-2 inhibitor
- EGFR INHIBITOR
- Epidermal growth factor receptor erbB1 inhibitor
- FLT1 INHIBITOR
- Vascular endothelial growth factor receptor inhibitor
- FLT4 INHIBITOR
- KDR INHIBITOR
- ERBB4 INHIBITOR
- Receptor protein-tyrosine kinase erbB-4 inhibitor
- FLT3 INHIBITOR
- VEGFR inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AAK1
- PKN1
- NUAK2
- OPA1
- PAICS
- PAK2
- PAK4
- PDGFRB
- PDXK
- PEBP1
- PFKP
- PHKG2
- PIM1
- PIP4K2A
- PIP4K2C
- PKMYT1
- PKN2
- PRKD3
- PLK4
- PRKAA1
- PRKACA
- PRKACB
- PRKACG
- PRKAG1
- PRKAG2
- PRKAR2A
- PRKCA
- PRKCB
- PRKCD
- PRKCI
- PRKCQ
- PRKCZ
- NQO2
- NLK
- NEK9
- NEK3
- MAP4K2
- MAP4K3
- MAP4K4
- MAP4K5
Cross-references
Synonyms
- Bms 6690514
- BMS 690514
- BMS690514
- VKU5X213Q7
- RefChem:569724
- DTXCID1022689
- Pan HER/VEGFR2 Receptor Tyrosine Kinase Inhibitor BMS-690514
- MFCD18633295
- C19H24N6O2
- EVRI
- UNII-VKU5X213Q7
- GTPL7879
- orb1707533
- SCHEMBL1219326
- SCHEMBL29385871
- BDBM185148
- EX-A11144
- NSC760765
- NSC799363
- BMS 690514 [WHO-DD]
- AKOS005266712
- AKOS015949393
- CS-0244
- NSC-760765
- NSC-799363
- NCGC00378630-01
- HY-10333
- MS-25905
- NS00072512
- P12423
- T14677
- F502781
- BRD-K76239644-001-01-8
- BRD-K76239644-001-02-6
- SCHEMBL1218633
- MFCD22124577
- CS-M1183
- SB21701
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