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TIDEGLUSIB
SynDRA canonical compound SYN0038232 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | GSK3B |
|---|
| Mechanism of action | glycogen synthase kinase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- GSK3B INHIBITOR
- Glycogen synthase kinase-3 beta inhibitor
- GSK3B IRREVERSIBLE INHIBITOR
- glycogen synthase kinase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HDAC6
- SYK
- AAK1
- PAK4
- PFKP
- PDXK
- PDGFRB
- PASK
- PAK6
- PAK2
- PHKG2
- PAICS
- OPA1
- OLA1
- NUAK2
- NTRK1
- NQO2
- PGRMC1
- PIM1
- NEK9
- PIP4K2C
- PRKCD
- PRKCB
- PRKCA
- PRKAR2A
- PRKAG2
- PRKAG1
- PRKACG
- PRKACB
- PRKACA
- PRKAA1
- PLK4
- PKN3
- PKN2
- PKN1
- PKMYT1
- NLK
- NEK3
- PRKCQ
- MAPK15
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- KSYK
- NSD2
- NTM1A
- NTMT1
- SARM1
Cross-references
Synonyms
- NP-031112
- NP-12
- NP031112
- TIDEGLUSIB (NP031112)
- Zentylor nypta
- Tideglusib(NP-031112)
- 4-Benzyl-2-(naphthalen-1-yl)-1,2,4-thiadiazolidine-3,5-dione
- Tideglusib [INN]
- NP 031112
- 4-benzyl-2-naphthalen-1-yl-1,2,4-thiadiazolidine-3,5-dione
- Q747Y6TT42
- 1,2,4-Thiadiazolidine-3,5-dione, 2-(1-naphthalenyl)-4-(phenylmethyl)-
- 2-(1-naphthalenyl)-4-(phenylmethyl)-1,2,4-thiadiazolidine-3,5-dione
- tideglusibum
- Zentylor
- Nypta
- UNII-Q747Y6TT42
- TIDEGLUSIB [WHO-DD]
- SCHEMBL676929
- GTPL6929
- CHEMBL3545157
- Tideglusib, >=98% (HPLC)
- DTXSID90235682
- EX-A600
- CHEBI:147398
- HMS3673G17
- HMS3744E05
- HMS3884J18
- 4-benzyl-2-(naphthalen-1-yl)-(1,2,4)thiadiazolidine-3,5-dione
- BCP06016
- Tideglusib,CAS:865854-05-3
- BDBM50166940
- MFCD18633296
- NSC800950
- s2823
- ZINC13985228
- AKOS025149085
- CCG-267855
- CS-0613
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