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RIPASUDIL
SynDRA canonical compound SYN0038149 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | ROCK2 |
|---|
| Mechanism of action | Rho associated kinase inhibitor |
|---|
| Indication | glaucoma | ocular hypertension |
|---|
| Disease area | ophthalmology |
|---|
All known targets
- ROCK2
- ROCK1
- PRKACA
- AURKB
- CDK9
- PRKD2
- PRKCD
- PRKAG1
- PRKAA1
- PLK4
- PKN2
- PKN1
Mechanisms of action (all sources)
- Rho associated kinase inhibitor
- ROCK2 INHIBITOR
- Rho-associated protein kinase inhibitor
- ROCK1 INHIBITOR
- PRKACA INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AAK1
- NAT10
- NEK1
- NEK2
- NEK3
- NEK7
- NEK9
- NLK
- NTRK1
- NUAK2
- OPA1
- PAICS
- PAK4
- PAK6
- PDGFRB
- PDXK
- PFKP
- PGRMC1
- PHKG2
- PIM1
- PIP4K2C
- PKMYT1
- PRKACB
- PRKACG
- PRKAG2
- PRKAR2A
- PRKCA
- PRKCB
- PRKCI
- NDUFA13
- MYLK3
- PRKD3
- MYLK
- MAP3K20
- MAP3K3
- MAP3K4
- MAP3K5
- MAP3K6
- MAP4K1
- MAP4K2
ATC classes
- S01E · ANTIGLAUCOMA PREPARATIONS AND MIOTICS
Cross-references
Synonyms
- ripasudil hydrochloride hydrate
- ripasudil hydrochloride
- glanatec
- glanatec ophthalmic solution
- ripasudil HCl
- K-321 anhydrous free base
- ripasudilum
- RefChem:179484
- DTXCID001509873
- K-115 free base
- k115 Free base
- Ripasudil free base
- Ripasudil [INN]
- UNII-11978226XX
- RIPASUDIL [MI]
- Ripasudil (USAN/INN)
- RIPASUDIL [USAN]
- RIPASUDIL [WHO-DD]
- K-115 anhydrous free base
- SCHEMBL31542
- C15H18FN3O2S
- orb1685487
- SCHEMBL29356679
- GTPL10423
- CHEBI:136046
- EX-A3647
- BDBM50087135
- HY-15685A
- MFCD28291829
- NSC800869
- AKOS027338679
- CS-3402
- EBC-237024
- NSC-800869
- NCGC00496843-01
- AC-36873
- AS-35170
- K-115 (ripasudil hydrochloride dihydrate)
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