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OCIFISERTIB
SynDRA canonical compound SYN0038138 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | PLK4 |
|---|
| Mechanism of action | serine/threonine kinase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- PLK4 INHIBITOR
- Serine/threonine-protein kinase PLK4 inhibitor
- serine/threonine kinase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AURKA
- AURKB
- CYP2C19
- CYP2C9
- CYP3A4
- FGFR1
- NTRK1
- NTRK2
- TEK
- CYP1A2
- CYP2D6
- FLT3
- PLK1
- PLK2
- PLK3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- CFI-400945 FREE BASE
- AK173721
- AKOS025396133
- Cfi-400945
- CFI-400945 (FREE BASE)
- OCIFISERTIB(CFI-400945 FREE BASE)
- CFI 400945
- CFI400945
- CFI-400945 free base
- TL1UD860AA
- UNII-TL1UD860AA
- CFI-400945 (free base)
- CFI-400945 (fumarate)
- ocifisertib [INN]
- orb1299868
- SCHEMBL9946383
- SCHEMBL29430199
- SCHEMBL30068088
- GTPL12083
- EX-A1609
- NSC791966
- s7552
- CCG-269938
- CS-5939
- NSC-791966
- SB17032
- CFI-400945,
- NCGC00487085-03
- AC-36327
- AS-35185
- DA-62221
- DA-62222
- HY-12300
- T7384
- C211324
- (2'S,3R)-2'-[3-[(E)-2-[4-[[(2S,6R)-2,6-dimethylmorpholin-4-yl]methyl]phenyl]ethenyl]-1H-indazol-6-yl]-5-methoxyspiro[1H-indole-3,1'-cyclopropane]-2-one
- RefChem:124745
- SCHEMBL29430184
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