← SynDRA

PILARALISIB

SynDRA canonical compound SYN0038125 — structure-anchored drug synonym record

All known targets

• PIK3CG
• PIK3CA
• PIK3CD
• PIK3CB
• PIK3R1
• PIK3R2
• PIK3R3
• PIK3R5

Mechanisms of action (all sources)

• PIK3R1 INHIBITOR
• PIK3CB INHIBITOR
• PIK3CG INHIBITOR
• PIK3CA INHIBITOR
• PIK3R2 INHIBITOR
• PIK3CD INHIBITOR
• PIK3R5 INHIBITOR
• PIK3R3 INHIBITOR
• PI3K inhibitor
• PIK3CG MODULATOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• PIK3C3
• PIK3CB
• PRKDC
• HDAC6
• MTOR

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• CP2C9
• CP3A7
• KSYK
• NSD2
• SYK

Cross-references

• PubChem CID: 56599306
• ChEMBL: CHEMBL3360203
• DrugBank: DB11772
• ChEBI: 71957
• TTD: D03KAC
• LINCS BRD: BRD-K49456274

Synonyms

• SAR-245408
• SAR245408
• XL-147
• XL147
• N-[3-(2,1,3-Benzothiadiazol-5-ylamino)quinoxalin-2-yl]-4-methylbenzenesulfonamide
• XL147 analogue
• PI3K inhibitor X
• XL 147
• Pilaralisib analogue
• N-[3-(2,1,3-Benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methylbenzenesulfonamide
• CHEBI:71957
• C21H16N6O2S2
• N-(3-(benzo[c][1,2,5]thiadiazol-5-ylamino)quinoxalin-2-yl)-4-methylbenzenesulfonamide
• Benzenesulfonamide, N-[3-(2,1,3-benzothiadiazol-5-ylamino)-2-quinoxalinyl]-4-methyl-
• PubChem22457
• XL-147 derivative 2
• cc-43
• AC1Q2LO8
• AC1LZ6F0
• SAR245408 + MSC1936369B
• SAR 245408
• Pilaralisib (XL147)
• 2-amino-N-[3-[[3-(2-chloro-5-methoxyanilino)quinoxalin-2-yl]sulfamoyl]phenyl]-2-methylpropanamide
• 60ES45KTMK
• 2-Amino-n-(3-(N-(3-((2-chloro-5-methoxyphenyl)amino)quinoxalin-2-yl)sulfamoyl)phenyl)-2-methylpropanamide
• UNII-60ES45KTMK
• 2-amino-N-(3-(N-(3-((2-chloro-5-methoxyphenyl)amino)quinoxalin-2-yl)sulfamoyl)phenyl)-2-methylpropanamide.
• Pilaralisib [USAN:INN]
• Pilaralisib [INN]
• PILARALISIB [USAN]
• PILARALISIB [WHO-DD]
• SCHEMBL189422
• CHEMBL3360203
• SCHEMBL14921345
• SCHEMBL16154579
• EX-A196
• DTXSID701025731
• AMY10846