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GLPG-0974
SynDRA canonical compound SYN0038116 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | FFAR2 |
|---|
| Mechanism of action | free fatty acid receptor antagonist |
|---|
| Indication | ulcerative colitis |
|---|
| Disease area | gastroenterology |
|---|
All known targets
Mechanisms of action (all sources)
- FFAR2 ANTAGONIST
- Free fatty acid receptor 2 antagonist
- free fatty acid receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADGRF1
- HRH2
- HRH4
- HTR1E
- HTR2A
- HTR2B
- HTR3A
- HTR5A
- HTR6
- KCNH2
- MBD4
- MPG
- MUTYH
- NEIL1
- NEIL2
- NR1I2
- NTHL1
- OGG1
- OPRD1
- OPRK1
- S1PR1
- SIGMAR1
- SLC6A3
- SMUG1
- TDG
- TMEM97
- TSPO
- HRH3
- HRH1
- ADRA1A
- GPR35
- ADRA1B
- ADRA1D
- ADRA2A
- ADRA2B
- ADRB1
- ADRB2
- ADRB3
- AGTR1
- APLNR
Cross-references
Synonyms
- GLPG 0974
- GLPG0974
- compound 99 [PMID 25380412]
- X7REK61AIS
- RefChem:143520
- MPMKMQHJHDHPBE-RUZDIDTESA-N
- A1LYD
- UNII-X7REK61AIS
- C25H25ClN2O4S
- GTPL8417
- orb1707266
- SCHEMBL11298599
- SCHEMBL29352637
- GLXC-10358
- EX-A2832
- RFC07661
- BDBM50032334
- MFCD28502087
- AKOS027470232
- EBC-521573
- SB16999
- AC-36690
- DA-73763
- HY-12940
- MS-29019
- CS-0012804
- G14486
- T15388
- 4-[[(2R)-1-(1-benzothiophene-3-carbonyl)-2-methylazetidine-2-carbonyl]-[(3-chlorophenyl)methyl]amino]butanoic acid
- SCHEMBL11304160
- BDBM50032340
Look up GLPG-0974 in the interactive SynDRA portal →