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TOVORAFENIB
SynDRA canonical compound SYN0038109 — structure-anchored drug synonym record
| Clinical phase | Phase 1/Phase 2 |
|---|
| Mechanism of action | RAF inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- RAF1 INHIBITOR
- RAF serine/threonine protein kinase inhibitor
- BRAF INHIBITOR
- ARAF INHIBITOR
- RAF inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- MAP3K1
- DDR1
- CLK1
- RIPK3
- FRK
- LIMK1
- MYLK
- SYK
- MAP2K4
- BCR
- EPHB6
- MAP3K20
- TGFBR2
- EPHB4
- PDGFRB
- DDR2
- WEE1
- MAPK14
- MAPK11
- EPHA1
- DYRK1A
- EPHA2
- ABL2
- ABL1
- PIM1
- PHKG2
- PIM2
- PGRMC1
- PFKP
- PEBP1
- PDXK
- PIP4K2A
- PIP4K2C
- PKN1
- PKMYT1
- PRKACB
- PKN2
- PKN3
- PLK4
- PRKAA1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- OJEMDA
- Ojemda
- BIIB-024
- MLN-2480
- Mln2480
- TAK-580
- BIIB024
- DAY-101
- DAY101
- MLN2480
- VWMJHAFYPMOMGF-ZCFIWIBFSA-N
- BIIB 024
- Tak-580
- UNII-ZN90E4027M
- ZN90E4027M
- AMG 2112819
- MLN 2480
- Tak 580
- DAY 101
- AMG-2112819
- TAK580
- CHEBI:167672
- RefChem:190502
- DTXCID4071502
- pan-RAF Kinase Inhibitor DAY101
- Tovorafenib [USAN]
- TAK-580 (MLN2480)
- MLN 2480(BIIB-024)
- C17H12Cl2F3N7O2S
- QOP
- Ojemda (TN)
- Tovorafenib [WHO-DD]
- TOVORAFENIB [INN]
- Tovorafenib (JAN/USAN/INN)
- GTPL9977
- SCHEMBL4206123
- SCHEMBL29370193
- SCHEMBL29558654
- EX-A940
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