GLPG-0187

SynDRA canonical compound SYN0038087 — structure-anchored drug synonym record

Clinical phase	Phase 1
Primary target(s)	ITGA1 \| ITGB1
Mechanism of action	integrin antagonist

All known targets

ITGA1
ITGB1

Mechanisms of action (all sources)

integrin antagonist

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

ITGA5
ITGAV
ITGB3
ITGB5
ITGB6
ITGB8
PARP1

Cross-references

PubChem CID: 53340771
ChEMBL: CHEMBL3319236
DrugBank: DB12297
TTD: D01TJY

Synonyms

GLPG0187
IRAMs (bone metastases), Galapagos
IRAMs (bone metastases), ProStrakan
Alpha-1/beta-3 integrin antagonists (bone metastases), Galapagos
Alpha-1/beta-3 integrin antagonists (bone metastases), ProStrakan
RefChem:143517
INTEGRIN RECEPTOR ANTAGONIST GLPG0187
UNII-43A5P87Z4T
orb1303014
SCHEMBL2372722
SCHEMBL29363387
SCHEMBL30250858
GLPG0187?
GLXC-10663
EX-A1730
BDBM50497714
AKOS040758577
CS-6476
NCGC00509997-01
AC-29869
AS-84051
DA-73762
HY-100506
NS00073356
T4259
SB40407
SCHEMBL275519

Look up GLPG-0187 in the interactive SynDRA portal →