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PF-5190457
SynDRA canonical compound SYN0038018 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | GHSR |
|---|
| Mechanism of action | growth hormone secretagogue receptor inverse agonist |
|---|
All known targets
Mechanisms of action (all sources)
- GHSR INVERSE AGONIST
- Ghrelin receptor inverse agonist
- GHSR ANTAGONIST
- growth hormone secretagogue receptor inverse agonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- HTR2B
- ADGRF1
- HDAC6
- TDG
- SMUG1
- S1PR1
- OGG1
- NEIL1
- MUTYH
- MPG
- MBD4
- GPR35
- ADRA2A
- GPR119
- GLP1R
- FPR2
- FFAR4
- CX3CR1
- CHRM2
- C5AR1
- APLNR
- AGTR1
- ADRB2
- UNG
Cross-references
Synonyms
- Pf-05190457
- PF 05190457
- FF33NL9U5G
- RefChem:172286
- UNII-FF33NL9U5G
- MFCD28411390
- C29H32N6OS
- GTPL9060
- orb1307892
- SCHEMBL2445443
- SCHEMBL29766846
- ZIUDADZJCKGWKR-AREMUKBSSA-N
- GLXC-07414
- GLXC-25339
- BDBM50019926
- AKOS034831614
- EBC-499104
- AC-36924
- DA-56719
- HY-12584
- MS-29520
- CS-0012053
- G14477
- T16508
- PF-05190457, >=95% (HPLC)
- BRD-K02554563-001-01-6
- PF-05190457
- PF-05190457?
- SCHEMBL2435827
- SB16996
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