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AZD-8330
SynDRA canonical compound SYN0037900 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | MAP3K1 |
|---|
| Mechanism of action | MEK inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- MAP2K1 INHIBITOR
- Dual specificity mitogen-activated protein kinase kinase 1 inhibitor
- MAP2K2 INHIBITOR
- Dual specificity mitogen-activated protein kinase kinase 2 inhibitor
- MEK inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SYK
- EIF2AK1
- MAP2K5
- AAK1
- PAK4
- PFKP
- PDXK
- PDGFRB
- PCYT1A
- PASK
- PAK2
- PHKG2
- PAICS
- OPA1
- OLA1
- NUAK2
- NTRK1
- NQO2
- PGRMC1
- PIM1
- NEK9
- PIP4K2A
- PIP4K2C
- PKMYT1
- PKN1
- PKN2
- PKN3
- PLK1
- PLK4
- PRKAA1
- PRKACA
- PRKACB
- PRKACG
- PRKAG1
- PRKAG2
- NLK
- NEK7
- PRKCA
- MARK3
- MAP4K3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- Azd8330
- ARRY-424704
- ARRY-704
- AZD8330
- AZD 8330
- UNII-G4990BOZ66
- 2-((2-fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide
- 2-(2-fluoro-4-iodophenylamino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide
- G4990BOZ66
- C16H17FIN3O4
- 2-[(2-fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxopyridine-3-carboxamide
- RWEVIPRMPFNTLO-UHFFFAOYSA-N
- ARRY 424704
- ARRY-424704, ARRY-704
- 2-(2-fluoro-4-iodoanilino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxopyridine-3-carboxamide
- AZD8330(ARRY-424704; ARRY-704)
- 2-((2-fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)-1,5-dimethyl-6-oxo-1,6-dihydropyridine-3-carboxamide.
- ARRY704
- MLS006011055
- SCHEMBL388533
- GTPL8474
- CHEMBL3182621
- CHEBI:91424
- DTXSID50235986
- AZD 8330 [WHO-DD]
- ARRY424704
- BCPP000359
- BDBM520648
- HMS3295M05
- HMS3655B04
- BCP02466
- EX-A2349
- NSC772563
- NSC799353
- s2134
- ZINC43152942
- AKOS027420927
- BCP9000368
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