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PF-03758309
SynDRA canonical compound SYN0037832 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | PAK4 |
|---|
| Mechanism of action | P21 activated kinase inhibitor |
|---|
All known targets
- PAK4
- LATS1
- PAK1
- PAK2
- PAK3
- PAK5
- PAK6
Mechanisms of action (all sources)
- P21 activated kinase inhibitor
- PAK4 INHIBITOR
- Serine/threonine-protein kinase PAK 4 inhibitor
- LATS1 INHIBITOR
- PAK1 INHIBITOR
- PAK2 INHIBITOR
- PAK3 INHIBITOR
- PAK5 INHIBITOR
- PAK6 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AAK1
- NEK9
- PFKP
- PEBP1
- PDXK
- PDK1
- PDGFRB
- PDGFRA
- PASK
- PAK6
- PAK5
- PAK3
- PAK2
- PAK1
- PAICS
- OPA1
- OLA1
- NUAK2
- NUAK1
- NTRK1
- NQO2
- PGRMC1
- PHKG1
- PHKG2
- PLK1
- PRKAG1
- PRKACG
- PRKACB
- PRKACA
- PRKAA2
- PRKAA1
- PLK4
- PLK3
- PKN3
- PIK3C2B
- PKN2
- PKN1
- PKMYT1
- PIP4K2C
- PIP4K2A
Cross-references
Synonyms
- PF-3758309
- PF-309
- PK459EA5I2
- example 114 [US8530652]
- PF3758309
- compound 1 [PMID: 24432870]
- example 114 (US8530652)
- compound 1 (PMID: 24432870)
- RefChem:860475
- MFCD18633226
- US8530652, 114
- UNII-PK459EA5I2
- C25H30N8OS
- 7KC
- GTPL8937
- orb1300605
- SCHEMBL1369342
- CHEBI:93751
- EX-A849
- BDBM101536
- BDBM101618
- GLXC-90543
- YKB04415
- NSC781470
- NSC800847
- s7094
- AKOS027422746
- CCG-269617
- CS-0773
- EBC-221084
- NSC-781470
- NSC-800847
- NCGC00345784-01
- NCGC00345784-03
- NCGC00345784-05
- NCGC00345784-12
- AC-33020
- AS-56208
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