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VS-4718
SynDRA canonical compound SYN0037785 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Mechanism of action | focal adhesion kinase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- PTK2 INHIBITOR
- Focal adhesion kinase 1 inhibitor
- FAK inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABL1
- LCK
- TNK2
- TEK
- SRC
- ROCK1
- RET
- RAF1
- PRKCA
- PDGFRB
- NTRK1
- NEK6
- MAPK9
- MAPK10
- MAPK1
- MAP2K1
- KIT
- ALK
- KDR
- JAK2
- INSR
- IGF1R
- HDAC6
- FYN
- FLT3
- FGFR1
- EPHA1
- EGFR
- DAPK1
- CSNK1G1
- CHEK1
- AURKA
- ZAP70
Cross-references
Synonyms
- PND-1186
- SR-2516
- PND 1186
- PND1186
- L2BD0MW4OL
- SR 2516
- RefChem:194644
- FAK Inhibitor VS-4718
- SR2516
- MFCD28125506
- PND-1186 (VS-4718)
- SR-2156
- UNII-L2BD0MW4OL
- SCHEMBL47360
- GTPL8742
- orb1307003
- SCHEMBL29381276
- SCHEMBL29478885
- SCHEMBL29493098
- Vs-4718(pnd1186)
- EX-A505
- GLXC-05729
- HMS3673G09
- BDBM50440659
- EBC-73186
- NSC783102
- PND-1186?
- s7653
- AKOS026750279
- CCG-269701
- CS-1584
- NSC-783102
- SB17061
- NCGC00378620-04
- AC-33052
- AS-55857
- DA-48063
- FP103465
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