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GOLVATINIB
SynDRA canonical compound SYN0037771 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | MET |
|---|
| Mechanism of action | VEGFR inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- VEGFR inhibitor
- MET INHIBITOR
- Hepatocyte growth factor receptor inhibitor
- KDR INHIBITOR
- Vascular endothelial growth factor receptor 2 inhibitor
- KDR MODULATOR
- MET MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- EPHA4
- LCK
- BCR
- MAP3K1
- MAP2K5
- PTK2B
- PTK6
- LYN
- STK24
- LIMK1
- FLT3
- MAP3K20
- FRK
- NTRK1
- EPHA2
- RET
- RIPK2
- RIPK3
- HCK
- PDGFRB
- TAOK2
- SYK
- ERN2
- ABL1
- MAPK14
- EPHB4
- EPHB6
- MAP4K5
- EPHB2
- EPHA7
- EIF2AK1
- EPHB3
- MST1R
- EPHA5
- ABL2
- DDR2
- DDR1
- TESK1
- PIP4K2A
- PIM1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- HLAB
- IFNB1
- KSYK
- NSD2
- TP53
Cross-references
Synonyms
- E-7050
- E-7050 (GOLVATINIB)
- E7050
- ER-396901-08
- GOLVATINIB (E7050)
- Golvatinib tartrate
- C-Met and VEGF-2 tyrosine kinase inhibitor (oral, cancer), Eisai
- Golvatinib (E7050)
- E 7050
- UNII-516Z3YP58E
- Golvatinib (USAN)
- Golvatinib [USAN]
- 1-N'-[2-fluoro-4-[2-[[4-(4-methylpiperazin-1-yl)piperidine-1-carbonyl]amino]pyridin-4-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
- 516Z3YP58E
- N-[2-Fluoro-4-[[2-[[[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl]amino]pyridin-4-yl]oxy]phenyl]-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
- Golvatinib [USAN:INN]
- N-(2-Fluoro-4-{[2-({[4-(4-methylpiperazin-1-yl)piperidin-1-yl]carbonyl}amino)pyridin-4-yl]oxy}phenyl)-N'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
- E7050;Golvatinib
- GOLVATINIB [INN]
- GOLVATINIB [WHO-DD]
- GTPL7956
- SCHEMBL1727298
- CHEMBL3039525
- DTXSID40239155
- EX-A830
- CHEBI:177746
- HMS3651J19
- BCP06122
- BDBM50100615
- MFCD22124462
- NSC800107
- NSC808608
- s2859
- ZINC43195317
- AKOS025404927
- CCG-270294
- CS-0595
- DB11977
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