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LCL-161
SynDRA canonical compound SYN0037527 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | BIRC2 | XIAP |
|---|
| Mechanism of action | XIAP inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- BIRC2 INHIBITOR
- XIAP INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABL1
- AURKA
- BIRC3
- BIRC7
- BRD4
- BRPF1
- CDK2
- CSNK1D
- CYP3A4
- FGFR3
- GSK3B
- HDAC6
- MAPK1
- TRIM24
Cross-references
Synonyms
- LCL161
- Nvp-lcl 161
- 6TNS415Y3P
- Smac Mimetic LCL161
- RefChem:152599
- DTXCID101510120
- MFCD23160049
- NVP-LCL161
- C26H33FN4O3S
- UNII-6TNS415Y3P
- GTPL7912
- orb1306530
- SCHEMBL1275369
- LCL 161 [WHO-DD]
- EX-A533
- CHEBI:193137
- GLXC-03701
- LCL-161?
- BDBM50441356
- NSC772868
- s7009
- AKOS027422741
- CCG-269696
- CS-1630
- NSC-772868
- NCGC00378579-04
- NCGC00378579-07
- NCGC00378579-08
- AC-32971
- BP-25378
- FL103735
- HY-15518
- SY069614
- L1044
- NS00073098
- T2080
- F861476
- BRD-K08248804-001-01-8
Look up LCL-161 in the interactive SynDRA portal →