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LY-2886721

SynDRA canonical compound SYN0037408 — structure-anchored drug synonym record

All known targets

• BACE1
• BACE2

Mechanisms of action (all sources)

• beta-secretase inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ABCB1
• CYP2C9
• CYP2D6
• CYP3A4
• HDAC6

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• KSYK
• SYK

Cross-references

• PubChem CID: 49837968
• ChEMBL: CHEMBL2396989
• DrugBank: DB12547
• PDB: 3YS
• TTD: D0F8GK

Synonyms

• LY2886721
• LY 2886721
• UNII-2CQ62IWB67
• 2CQ62IWB67
• N-(3-((4aS,7aS)-2-amino-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl)-5-fluoropicolinamide
• CHEMBL2396989
• N-{3-[(4as,7as)-2-Amino-4a,5-Dihydro-4h-Furo[3,4-D][1,3]thiazin-7a(7h)-Yl]-4-Fluorophenyl}-5-Fluoropyridine-2-Carboxamide
• n-(3-((4as,7as)-2-amino-4a,5-dihydro-4h-furo(3,4-d)(1,3)thiazin-7a(7h)-yl)-4-fluorophenyl)-5-fluoro-2-pyridinecarboxamide
• NIDRNVHMMDAAIK-YPMLDQLKSA-N
• MLS006011070
• SCHEMBL966802
• GTPL6475
• RefChem:154547
• DTXCID9077608
• MFCD22124078
• C18H16F2N4O2S
• orb1301111
• SCHEMBL30477100
• EX-A029
• GLXC-05140
• HMS3884J09
• BDBM50012647
• s2156
• AKOS027422646
• LY 2886721 - Bio-X trade mark
• CCG-268530
• CS-0458
• NCGC00346506-04
• NCGC00346506-07
• AC-33097
• AS-56127
• BL300094
• FL103714
• HY-13240
• SMR004702860
• LY2886721?
• NS00072934
• T6058
• 3YS