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SCH-900776
SynDRA canonical compound SYN0037376 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | CHEK1 |
|---|
| Mechanism of action | CHK inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- CHK inhibitor
- CHEK1 INHIBITOR
- Serine/threonine-protein kinase Chk1 inhibitor
- CHK1 inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AAK1
- PAICS
- PDXK
- PDGFRB
- PASK
- PAK6
- PAK4
- PAK2
- OPA1
- PGRMC1
- OLA1
- NUAK2
- NTRK1
- NQO2
- NLK
- NEK9
- PEBP1
- PHKG2
- NEK3
- PRKACA
- PRKCA
- PRKAR2A
- PRKAG2
- PRKAG1
- PRKACG
- PRKACB
- PRKAA1
- PIM1
- PLK4
- PKN2
- PKN1
- PKMYT1
- PIP4K2C
- PIP4K2A
- NEK7
- NEK2
- MAP3K6
- MAPK14
- MAPKAPK2
- MAPK9
Cross-references
Synonyms
- SCH 900776
- Mk-8776
- CHEMBL1643208
- MK 8776
- 6-bromo-3-(1-methyl-1H-pyrazol-4-yl)-5-(piperidin-3-yl)pyrazolo[1,5-a]pyrimidin-7-amine
- GTPL7943
- SCHEMBL10380123
- CHEBI:131165
- HMS3656J19
- BCP02883
- BDBM50334854
- AKOS026750519
- NCGC00387868-02
- DA-40779
- 4CA-1150
- BCP0726000317
- J3.517.083I
- 891494-63-6 pound not SCH900776 pound not SCH-900776
- 6-bromo-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[5,1-b]pyrimidin-7-amine
- 6-bromo-3-(1-methylpyrazol-4-yl)-5-[(3S)-piperidin-3-yl]pyrazolo[1,5-a]pyrimidin-7-amine
- MK-8776 Racemate
- MK-8776 S-isomer
- SCH900776 (Racemate)
- 6-bromo-3-(1-methylpyrazol-4-yl)-5-piperidin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine
- SCH900776 S-isomer
- 6-BROMO-3-(1-METHYLPYRAZOL-4-YL)-5-[(3R)-PIPERIDIN-3-YL]PYRAZOLO[1,5-A]PYRIMIDIN-7-AMINE
- NSC764659
- NSC-764659
- FT-0700501
- FT-0771683
- Q27086899
- SCH 900776 (CAS:891494-64-7)
- SCH900776
- MK-8776
- K2ZSF0992C
- MK8776
- RefChem:159222
- CHK1 Inhibitor MK-8776
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