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VALBENAZINE
SynDRA canonical compound SYN0037201 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | SLC18A2 |
|---|
| Mechanism of action | vesicular monoamine transporter inhibitor |
|---|
All known targets
- SLC18A2
- KCNH2
- Slc18a2
- SLC18A1
- DRD2
- ADRA2A
- ADRA2C
- SCN1A
- SCN2A
- SCN3A
Mechanisms of action (all sources)
- SLC18A2 INHIBITOR
- Synaptic vesicular amine transporter inhibitor
- vesicular monoamine transporter inhibitor
- SLC18A2 ANTAGONIST
- SLC18A2 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR1A
- PTGS1
- ABL1
- PDE3A
- HRH3
- HTR2B
- MAOA
- MAPK1
- OPRM1
- PDE4A
- ACHE
- PGR
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- GSK3B
- FGFR2
- F2
- ESR1
- DRD3
- DRD1
- CSNK1D
- CHRM2
- CHRM1
- CDK2
- BRPF1
- BRD4
- AURKA
- AR
- ADRA2A
- ADRA1A
- ADORA3
- TRIM24
Drug classes
- Vesicular Monoamine Transporter 2 Inhibitors
- Vesicular Monoamine Transporter 2 Inhibitor
- Adrenergic Agents
- Adrenergic Uptake Inhibitors
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
ATC classes
- N07X · OTHER NERVOUS SYSTEM DRUGS
Cross-references
Synonyms
- INGREZZA
- INGREZZA SPRINKLE
- Ingrezza
- VALBENAZINE TOSYLATE
- valbenazine tosylate
- ingrezza
- NBI 98854
- valbenazine ditosylate
- dysval
- Valbenazina
- Mt-5199
- NBI-98854
- NBI-98782
- Vesicular monoamine transporter 2 inhibitor (CNS indications), Neurocrine
- VMAT-2 inhibitor (CNS disease), Neurocrine
- Valbenazine Tosylate
- Valbenazine ditosylate
- UNII-5SML1T733B
- 5SML1T733B
- Valbenazine tosylate [USAN]
- Valbenazine tosylate (USAN)
- NBI-98854 ditosylate
- UNII-54K37P50KH
- Valbenazine free base
- 54K37P50KH
- 1025504-45-3 (free base)
- Valbenazine [USAN:INN]
- ValbenazineNBI-98854
- Valbenazine (USAN/INN)
- GTPL8694
- CHEMBL2364639
- SCHEMBL15932979
- EX-A2002
- MFCD28963976
- ZINC43195697
- CS-5908
- DB11915
- SB17456
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