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LATANOPROSTENE BUNOD
SynDRA canonical compound SYN0037178 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | GUCY1A1 | PTGFR |
|---|
| Mechanism of action | prostanoid receptor agonist |
|---|
| Indication | intraocular pressure |
|---|
| Disease area | ophthalmology |
|---|
All known targets
- PTGFR
- GUCY1A1
- PTGER1
- PTGER3
Mechanisms of action (all sources)
- PTGFR AGONIST
- Prostanoid FP receptor agonist
- prostanoid receptor agonist
- PTGFR FULL AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- ADORA1
- SLC6A4
- SLC6A3
- SLC6A2
- PTGS1
- PGR
- PDE4A
- PDE3A
- OPRM1
- MAOA
- HTR2B
- HTR1A
- HRH3
- F2
- ESR1
- DRD3
- DRD1
- CHRM2
- CHRM1
- AR
- ADRA2A
- ADRA1A
- TBXA2R
Drug classes
- Prostaglandin Analog
- Ophthalmic Solutions
- Pharmaceutical Solutions
ATC classes
- S01E · ANTIGLAUCOMA PREPARATIONS AND MIOTICS
Cross-references
Synonyms
- VYZULTA
- Vyzulta
- NCX 116
- BOL-303259-X
- PF-3187207
- vyzulta
- Latanoprosteno bunod
- NCX-116
- NCX116
- Vesneo
- Latanoprostene bunod)
- PF-03187207
- BOL-303259-X1
- NO donors (glaucoma), NicOx/Pfizer
- NO-donating prostaglandin F2-alpha analogs (glaucoma), Pfizer
- NO-donating prostaglandin F2-alpha analogs (glaucoma), NicOx/Pfizer
- Nitric oxide-donating prostaglandin F2-alpha analogs (eye disease), NicOx/Pfizer
- NO-donating prostaglandin F2-alpha analogs (glaucoma), NicOx/ Bausch & Lomb
- I6393O0922
- latanoprosteno bunod
- latanoprostenum bunodum
- RefChem:58122
- DTXCID501513340
- Latanoprostene BUNOD [INN]
- UNII-I6393O0922
- Latanoprostene BUNOD [USAN:INN]
- Vyzulta (TN)
- MFCD30532608
- GTPL9635
- orb1308136
- Latanoprostene bunod (Standard)
- SCHEMBL12119560
- LATANOPROSTENE BUNOD [MI]
- CHEBI:177703
- Latanoprostene bunod (USAN/INN)
- LATANOPROSTENE BUNOD [USAN]
Reported adverse events
- Asthma
- Chest pain
- Dizziness
- Dry eye
- Myalgia
- Photophobia
- Eye pain
- Foreign body
- Punctate keratitis
- Blepharitis
- Infection
- Eyelid margin crusting
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