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AZD-8797
SynDRA canonical compound SYN0037128 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | CX3CR1 | CXCR1 | CXCR2 |
|---|
| Mechanism of action | CC chemokine receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- CC chemokine receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- ADGRF1
- CCR6
- SLC6A3
- SLC6A2
- S1PR1
- GPR35
- GPR119
- GLP1R
- FPR2
- FFAR4
- CXCR5
- CCR5
- CCR4
- CCR3
- C5AR2
- C5AR1
- C3AR1
- APLNR
- AGTR1
- ADRB2
- ADRA2A
- SLC6A4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- COMT
- GAMT
- GNMT
- HNMT
- KSYK
- NNMT
- NSD2
- PNMT
- SYK
Cross-references
Synonyms
- Kand-567
- Kand567
- AZD8797
- Rugocrixan
- AZD 8797
- S9Y83SS7PQ
- RefChem:930995
- KAND567
- KAND-567
- rugocrixan [INN]
- MFCD28139065
- CX3CR1 antagonist 18a
- SCHEMBL213194
- orb1707606
- SCHEMBL29473543
- C19H25N5OS2
- GTPL13739
- EX-A9889
- LLB71590
- AZD8797( KAND567)
- BDBM50432452
- AKOS030525989
- CS-6469
- compound 18a [PMID: 23516963]
- Fractalkine Receptor Antagonist KAND567
- NCGC00386735-01
- DA-61387
- HY-13848
- MS-26892
- E99040
- T14384
- AZD8797 hydrochloride
- SCHEMBL23828002
- KAND-567 hydrochloride
- KAND567 hydrochloride
- AZD-8797 hydrochloride
- TYJ65L5BK6
- SCHEMBL30288320
- SCHEMBL212398
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