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VISTUSERTIB
SynDRA canonical compound SYN0036993 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | MTOR |
|---|
| Mechanism of action | mTOR inhibitor |
|---|
All known targets
- MTOR
- MAPKAP1
- MTOR-RPTORA-MLST8-KT1S1-DEPTOR
Mechanisms of action (all sources)
- MTOR inhibitor
- Serine/threonine-protein kinase mTOR inhibitor
- MAPKAP1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- FECH
- PIK3CA
- PIK3CB
- PIK3CD
- PIK3CG
- SYK
- PFKP
- PASK
- PDXK
- PDGFRB
- PCYT1A
- AAK1
- PAK6
- PAK4
- PAK2
- PAICS
- OPA1
- OLA1
- NUAK2
- NTRK1
- PEBP1
- PI4KB
- PGRMC1
- PKN2
- PRKACB
- PRKACA
- PRKAA1
- PLK4
- PLK1
- PKN3
- PKN1
- PHKG2
- PKMYT1
- PIP4K2C
- PIP4K2A
- PIM1
- PIK3C3
- NLK
- NQO2
- NEK9
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP2C9
- CP2D6
- CP3A7
- KSYK
- MLST8
- NSD2
- PIK3R1
- RPTOR
Cross-references
Synonyms
- AZD-2014
- AZD2014
- CC-551
- VISTUSERTIB (AZD2014)
- AZD 2014
- UNII-0BSC3P4H5X
- 0BSC3P4H5X
- cc-551
- 3-[2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido[5,6-e]pyrimidin-7-yl]-N-methylbenzamide
- CHEMBL2336325
- 3-[2,4-Bis((3S)-3-methyLmorpholin-4-yl)pyrido-[5,6-e]pyrimidin-7-yl]-N-methylbenzamide
- C25H30N6O3
- 3-(2,4-bis((S)-3-methylmorpholino)pyrido[2,3-d]pyrimidin-7-yl)-N-methylbenzamide
- 3-[2,4-bis[(3S)-3-methylmorpholin-4-yl]pyrido[2,3-d]pyrimidin-7-yl]-N-methylbenzamide
- Vistusertib [INN]
- Vistusertib [USAN]
- Vistusertib (JAN/INN)
- Vistusertib (AZD-2014)
- vistusertib (AZD2014)
- Benzamide, 3-(2,4-bis((3S)-3-methyl-4-morpholinyl)pyrido(2,3-d)pyrimidin-7-yl)-N-methyl-
- 3-(2,4-Bis((3S)-3-methylmorpholin-4-yl)pyrido(5,6-e)pyrimidin-7-yl)-N-methylbenzamide
- Benzamide, 3-[2,4-bis[(3S)-3-methyl-4-morpholinyl]pyrido[2,3-d]pyrimidin-7-yl]-N-methyl-
- VISTUSERTIB [JAN]
- Vistusertib [USAN:INN]
- VISTUSERTIB [WHO-DD]
- MLS006011011
- SCHEMBL290672
- GTPL7699
- DTXSID20143584
- EX-A155
- AMY24188
- BCP05748
- BDBM50429701
- MFCD22628784
- NSC767189
- NSC780879
- NSC787289
- NSC799345
- s2783
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