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SB-743921
SynDRA canonical compound SYN0036678 — structure-anchored drug synonym record
| Clinical phase | Phase 1/Phase 2 |
|---|
| Primary target(s) | KIF11 |
|---|
| Mechanism of action | Kinesin-like spindle protein inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- Kinesin-like spindle protein inhibitor
- KIF11 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CYP3A4
- KCNH2
- CYP1A2
- CYP2C19
- CYP2C9
- CYP2D6
- HDAC6
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ABCB5
- IFNG
- KSYK
- MDR1
- MITF
- NSD2
- PARP1
- SYK
- TFE3
Cross-references
Synonyms
- SB-743921 FREE BASE
- N-[1-(3-benzyl-7-chloro-4-oxo-quinazolin-2-yl)propyl]-4-bromo-N-(3-dimethylaminopropyl)benzamide
- SB-743921 free base
- UNII-24DSZ1VN92
- SB 743921 [WHO-DD]
- RefChem:181585
- KSP Inhibitor SB-743921
- SB743921
- SB-743921 (free base)
- SCHEMBL645543
- orb1699380
- SCHEMBL29377772
- CHEBI:231716
- BDBM50427294
- AKOS040749430
- NCGC00346571-01
- NCGC00346571-06
- NCGC00346571-08
- DA-77721
- HY-14661
- CS-0003505
- T28694
- BRD-K68532323-003-02-8
- BRD-K68532323-003-05-1
- N-(3-aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxo-4H-chromen-2-yl)-2-methylpropyl]-4-methylbenzamide
- SB743921 hydrochloride, >=98% (HPLC)
- GLXC-07340
- SB 743921?
- EX-A2156
- 2YW6FB68GM
- CCG-270018
- MFCD18385010
- SCHEMBL644065
- QMB92933
- SB-743921 hydrochloride
- DB-353608
- AC-35953
- C31H34Cl2N2O3
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