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APROCITENTAN
SynDRA canonical compound SYN0034085 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | EDNRA | EDNRB |
|---|
| Mechanism of action | endothelin receptor antagonist |
|---|
| Indication | pulmonary arterial hypertension (PAH) |
|---|
| Disease area | pulmonary |
|---|
All known targets
Mechanisms of action (all sources)
- EDNRB ANTAGONIST
- Endothelin receptor, ET-A/ET-B antagonist
- EDNRA ANTAGONIST
- endothelin receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
ATC classes
- C02K · OTHER ANTIHYPERTENSIVES
Cross-references
Synonyms
- TRYVIO
- Tryvio
- ACT-132577
- Macitentan metabolite m6
- Jeraygo
- ACT 132577
- UNII-MZI81HV01P
- Despropyl Macitentan
- MZI81HV01P
- CHEMBL2165326
- CHEBI:76609
- Macitentan metabolite
- SCHEMBL3646065
- ZINC95553608
- BDBM50395672
- AKOS028114466
- CS-2687
- HY-15895
- BC600808
- aprocitentanum
- RefChem:558448
- N-Despropyl-macitentan
- Aprocitentan [USAN]
- MFCD28155267
- Macitentan Impurity 24
- Tryvio (TN)
- Aprocitentan [WHO-DD]
- Aprocitentan (USAN/INN)
- APROCITENTAN [INN]
- C16H14Br2N6O4S
- orb1299478
- Aprocitentan (ACT-132577)
- SCHEMBL30439551
- GTPL10070
- Aprocitentan (ACT-132577)?
- GLXC-08039
- DUB52245
- EX-A4419
- ACT132577
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