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ELIGLUSTAT
SynDRA canonical compound SYN0033293 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | UGCG |
|---|
| Mechanism of action | glycosyl transferase inhibitor |
|---|
| Indication | Gaucher disease |
|---|
| Disease area | hematology |
|---|
All known targets
Mechanisms of action (all sources)
- UGCG INHIBITOR
- Ceramide glucosyltransferase inhibitor
- glycosyl transferase inhibitor
- UGCG MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABL1
- ACHE
- HRH3
- HTR1A
- HTR2B
- MAOA
- MAPK1
- NTMT1
- OPRM1
- PDE3A
- PDE4A
- PGR
- PTGS1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- HDAC6
- GSK3B
- FGFR2
- BRPF1
- ADORA1
- ADRA1A
- ADRA2A
- AR
- AURKA
- BRD4
- CDK2
- F2
- CHRM1
- CHRM2
- CSNK1D
- DRD1
- DRD3
- ESR1
- TRIM24
Drug classes
- Glucosylceramide Synthase Inhibitors
- Enzyme Inhibitors
- Glucosylceramide Synthase Inhibitor
- Cytochrome P450 2D6 Inhibitors
- P-Glycoprotein Inhibitors
ATC classes
- A16A · OTHER ALIMENTARY TRACT AND METABOLISM PRODUCTS
Cross-references
Synonyms
- CERDELGA
- Cerdelga
- ELIGLUSTAT TARTRATE
- cerdelga
- Genz-99067
- eliglustat tartrate
- Genz-112638
- GENZ-99067
- Eliglustat tartrate
- Fabrazyme (TN)
- Genz 99067
- DR40J4WA67
- CHEBI:82752
- Eliglustatum
- RefChem:56880
- A16AX10
- DTXCID301391881
- MFCD19443735
- Eliglustat free base
- Eliglustat [USAN:INN]
- UNII-DR40J4WA67
- C23H36N2O4
- ELIGLUSTAT [MI]
- ELIGLUSTAT [INN]
- Eliglustat (USAN/INN)
- ELIGLUSTAT [USAN]
- ELIGLUSTAT [VANDF]
- Eliglustat; Genz 99067
- ELIGLUSTAT [WHO-DD]
- Eliglustat(Genz-99067)?
- SCHEMBL421755
- GTPL7536
- orb1303942
- SCHEMBL29701229
- GLXC-90436
- EX-A2301
- EBC-26968
Reported adverse events
- Arthralgia
- Dyspepsia
- Fatigue
- Headache
- Palpitations
- Asthenia
- Back pain
- Constipation
- Cough
- Dizziness
- Flatulence
- Migraine
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