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IGURATIMOD
SynDRA canonical compound SYN0032976 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | PTGS2 |
|---|
| Mechanism of action | Cyclooxygenase inhibitor |
|---|
| Indication | rheumatoid arthritis |
|---|
| Disease area | rheumatology |
|---|
All known targets
Mechanisms of action (all sources)
- NFKB pathway inhibitor
- Cyclooxygenase inhibitor
- MIF INHIBITOR
- Macrophage migration inhibitory factor inhibitor
- TRAF3IP2 INHIBITOR
- E3 ubiquitin ligase TRAF3IP2 inhibitor
- PTGS2 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PDE4A
- PTGS1
- PDE4D
- ADORA3
- SLC6A2
- SLC6A3
- PGR
- SLC6A4
- KCNH2
- PDE3A
- OPRM1
- OPRD1
- NR1I2
- MC3R
- MAOA
- KDR
- ACHE
- HTR2B
- HTR1A
- HRH3
- HRH1
- HDAC6
- F2
- ESR1
- DRD3
- DRD1
- CHRM2
- CHRM1
- AR
- ADRA2C
- ADRA2A
- ADRA1A
- TBXA2R
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- kolbet
- careram
- T-614
- Careram
- Kolbet
- T 614
- 4IHY34Y2NV
- DTXCID3028897
- iguratimodum
- RefChem:790583
- Iguratimod [INN]
- Iremod
- MFCD00882374
- C17H14N2O6S
- NCGC00181783-02
- T614
- UNII-4IHY34Y2NV
- Colvet
- Iguratimod?
- ANMATWQYLIFGOK-UHFFFAOYSA-N
- Iguratimod (Standard)
- IGURATIMOD [MI]
- Iguratimod (JAN/INN)
- IGURATIMOD [JAN]
- IGURATIMOD [WHO-DD]
- SCHEMBL26326
- GTPL9736
- Iguratimod - Bio-X trade mark
- orb1302153
- Iguratimod, >=98% (HPLC)
- SCHEMBL29366981
- CHEBI:31689
- GLXC-07102
- HMS5085A07
- Tox21_113422
- BDBM50458537
- EBC-46041
- HY-17009R
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