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CADRALAZINE
SynDRA canonical compound SYN0032246 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | CACNA1C |
|---|
| Mechanism of action | adrenergic receptor antagonist |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
Mechanisms of action (all sources)
- adrenergic receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PTGS2
- ADORA1
- NR1I2
- HRH3
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MLNR
- NPY1R
- NR3C1
- ADORA2A
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- HRH2
- HRH1
- HDAC6
- GHSR
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
- AVPR2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Antihypertensive Agents
- Cardiovascular Agents
- Vasodilator Agents
ATC classes
- C02D · ARTERIOLAR SMOOTH MUSCLE, AGENTS ACTING ON
Cross-references
Synonyms
- cadrilan
- cadral
- cadraten
- Cadralazina
- Cadral
- CGP-18684
- CGP-22639
- DC-826
- ISF-2405
- ISF-2469
- Cadralazinum
- Ethyl 6-(ethyl(2-hydroxypropyl)amino)-3-pyridazinecarbazate
- 8T96I3U713
- DTXCID1028651
- RefChem:573306
- C02DB04
- C12H21N5O3
- NCGC00182063-02
- Cadraten
- Cadrilan
- Cadraten; Cadrilan; DC 826; ISF 2469; Presmode
- Cadralazina [Spanish]
- Cadralazinum [INN-Latin]
- Cadralazina [INN-Spanish]
- Cadralazine [INN:BAN:JAN]
- CAS-64241-34-5
- BRN 0894631
- Cadralazine?
- UNII-8T96I3U713
- Cadral (TN)
- MFCD00865833
- CADRALAZINE [MI]
- CADRALAZINE [INN]
- CADRALAZINE [JAN]
- Cadralazine (JP17/INN)
- CADRALAZINE [MART.]
- SCHEMBL48939
- CADRALAZINE [WHO-DD]
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