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LYMECYCLINE
SynDRA canonical compound SYN0030104 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Mechanism of action | bacterial 50S ribosomal subunit inhibitor |
|---|
| Indication | acne vulgaris (AV) |
|---|
| Disease area | dermatology |
|---|
All known targets
- Stap-coc pbp2
- rpsD
- rpsI
- SNCA
Mechanisms of action (all sources)
- bacterial 50S ribosomal subunit inhibitor
- Stap-coc pbp2 BINDER
- bacterial 30S ribosomal subunit inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- PTGS2
- ADORA1
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MC4R
- MLNR
- NPY1R
- NR3C1
- ADORA2A
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- HTR1A
- HRH3
- HRH2
- BDKRB2
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
- AVPR2
- CCKAR
Drug classes
- Anti-Bacterial Agents
- Anti-Infective Agents
- Tetracycline-class Antimicrobial
- Enzyme Inhibitors
- Protein Synthesis Inhibitors
ATC classes
- J01A · TETRACYCLINES
- D06A · ANTIBIOTICS FOR TOPICAL USE
- S03A · ANTIINFECTIVES
- A01A · STOMATOLOGICAL PREPARATIONS
- DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
- COMBINATIONS OF ANTIBACTERIALS
Cross-references
Synonyms
- mucomycin
- ciclolysine
- Tetracycline-L-methylenelysine
- tetracyclinemethylenelysine
- Limeciclina
- Ciclolysal
- Ciclolysine
- Mucomycin
- Tetracycline-l-methylenelysine
- Tetracyclinemethylenelysine
- Tetralysal
- Tetralysal 150
- Tetralysal 300
- Aureociclin
- Aureomicina
- Aurofac
- Biovetin
- Centraureo
- Chlortetracyclin
- Chrusomykine
- Lymecyclinum
- Orospray
- Acronize PD
- Aurofac 10
- Tetrlysal 300
- Lymecycline (INN)
- Tetralysal 300 (TN)
- N(2)-(((+)-5-Amino-5-carboxypentylamino)methyl)tetracycline
- N(6)-[({[(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracen-2-yl]carbonyl}amino)methyl]-L-lysine
- (+)-N-(5-Amino-5-carboxypentylaminomethyl)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide
- N-Lysinomethyltetracycline
- tetracycline-L Methylene-Lysine
- Lymecycline (85%)
- 7D6EM3S13P
- Tetralisal
- Armyl
- LYMECYCLINE [INN]
- Infaciclina
Reported adverse events
- Hypersensitivity
- Onycholysis
- Urticaria
- Headache
- Nausea
- Rash
- Dizziness
- Pancreatitis
- Asthenia
- Constipation
- Dyspepsia
- Flatulence
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