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AVATROMBOPAG
SynDRA canonical compound SYN0030081 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | MPL |
|---|
| Mechanism of action | thrombopoietin receptor agonist |
|---|
| Indication | thrombocytopenia |
|---|
| Disease area | hematology |
|---|
All known targets
Mechanisms of action (all sources)
- MPL AGONIST
- Thrombopoietin receptor agonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- HTR7
- NPY1R
- MLNR
- MC4R
- MC3R
- MAOA
- KCNH2
- HTR6
- HRH2
- HTR5A
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- NPY2R
- NTSR1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4A
- PDE4D
- PDE6A
- PGR
- PTGS1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TACR1
- TACR2
- HRH3
- HRH1
- ADORA1
- ADRB2
- CHRM1
- CCKBR
- BDKRB1
ATC classes
- B02B · VITAMIN K AND OTHER HEMOSTATICS
Cross-references
Synonyms
- DOPTELET
- DOPTELET SPRINKLE
- Doptelet
- avatrombopag maleate
- E5501
- E5501 maleate
- AKR-501
- YM477
- doptelet
- Akr-501
- E-5501
- YM-301477
- YM-477
- AS 1670542
- AKR 501
- UNII-3H8GSZ4SQL
- 3H8GSZ4SQL
- Avatrombopag [USAN:INN]
- Avatrombopag (USAN/INN)
- GTPL9953
- DTXSID30205667
- ZINC72190218
- AKOS027323962
- CS-3397
- HY-13463
- FT-0728753
- D10306
- AS1670542
- YM 477
- E 5501
- AKR501
- avatrombopagum
- RefChem:57776
- B02BX08
- DTXCID60128158
- Avatrombopag free base
- MFCD18633249
Reported adverse events
- Arthralgia
- Epistaxis
- Fatigue
- Headache
- Hypersensitivity
- Infection
- Nausea
- Pain
- Petechiae
- Pyrexia
- Cough
- Nasopharyngitis
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