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FOSTAMATINIB
SynDRA canonical compound SYN0030034 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx |
|---|
| Primary target(s) | FLT3 | SYK |
|---|
| Mechanism of action | SYK inhibitor |
|---|
| Indication | chronic immune thrombocytopenia (ITP) |
|---|
| Disease area | hematology |
|---|
All known targets
- SYK
- FLT3
- AAK1
- PDGFRB
- PIP4K2B
- PIK3CD
- PI4KB
- PHKG2
- PDPK1
- PDGFRA
- PIP5K1A
- PAK6
Mechanisms of action (all sources)
- SYK INHIBITOR
- Tyrosine-protein kinase SYK inhibitor
- FLT3 INHIBITOR
- RET INHIBITOR
- SYK MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACAD10
- PDXK
- NLK
- NQO2
- OLA1
- OPA1
- PAICS
- PASK
- PCYT1A
- PEBP1
- NAT10
- PFKP
- PGRMC1
- PIM1
- PIP4K2A
- PKMYT1
- PRKACG
- PRKAG1
- NDUFA13
- MYLK3
- PRKAR2A
- MAPK3
- MAP3K5
- MAP3K6
- MAP4K4
- MAP4K5
- MAPK1
- MAPK11
- MAPK14
- MAPK7
- MYH14
- MAPKAPK2
- MAPKAPK5
- MAT2A
- MCM4
- MDN1
- MELK
- MTREX
- PRKAG2
- PRKCA
ATC classes
- B02B · VITAMIN K AND OTHER HEMOSTATICS
Cross-references
Synonyms
- TAVALISSE
- Tavalisse
- tavlesse
- fostamatinib disodium
- tavalisse
- R935788
- R788
- R-788
- R-788 FREE ACID
- R-935788
- R-935788 FREE ACID
- R788 FREE ACID
- R935788 FREE ACID
- Fostamatinib disodium
- R788(prodrug of R406)
- R788 (Fostamatinib) Disodium
- UNII-X9417132K8
- R 788 sodium
- R788(Fostamatinib disodium)
- R 935788 sodium
- R935788 (Fostamatinib disodium, R788)
- R788 disodium
- X9417132K8
- R788 disodium hexahydrate
- R788 SODIUM
- R-788 disodium
- R788, Fostamatinib
- Tube731
- Disodium (6-(5-fluoro-2-(3
- UNII-SQ8A3S5101
- R-788 Free acid
- R-935788 Free acid
- SQ8A3S5101
- R7935788
- Fostamatinib [USAN:INN]
- R 788
- fostamatinibum
- RefChem:57243
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