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RACECADOTRIL
SynDRA canonical compound SYN0029999 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | MME |
|---|
| Mechanism of action | Enkephalinase inhibitor |
|---|
| Indication | diarrhea |
|---|
| Disease area | gastroenterology |
|---|
All known targets
Mechanisms of action (all sources)
- Enkephalinase inhibitor
- MME INHIBITOR
- Neprilysin inhibitor
- Membrane metalloendopeptidase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- OPRK1
- RARG
- NR1I2
- NR1H2
- NR3C1
- MAOA
- MC3R
- KCNH2
- OPRD1
- MLNR
- NPY1R
- HTR3A
- NR1H3
- NR1H4
- HTR2C
- NR1I3
- MC4R
- ABCB11
- HTR2A
- OPRM1
- PDE3A
- PDE4D
- PGR
- PPARA
- PTGS2
- RARA
- RARB
- SAMHD1
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- HTR2B
- HTR1A
- ABCC3
- CCKAR
- ADORA1
- ADORA2A
- ADORA3
- ADRA1A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Antidiarrheals
- Enzyme Inhibitors
- Gastrointestinal Agents
- Protease Inhibitors
ATC classes
- A07X · OTHER ANTIDIARRHEALS
Cross-references
Synonyms
- ecadotril
- acetorphan
- cadotril
- redotil
- Racecadotrilo
- Acetorphan
- Tiorfan
- Tiorfix
- NSC-759828
- Hidrasec
- Benzyl 2-(3-(acetylthio)-2-benzylpropanamido)acetate
- Racecadotril [INN]
- S049; Sinorphan
- NSC 759828
- 76K53XP4TO
- benzyl 2-[[2-(acetylsulfanylmethyl)-3-phenylpropanoyl]amino]acetate
- benzyl (3-(acetylthio)-2-benzylpropanoyl)glycinate
- Racecadotril (INN)
- Glycine, N-[2-[(acetylthio)methyl]-1-oxo-3-phenylpropyl]-,phenylmethyl ester [CAS]
- Glycine, N-[(2R)-2-[(acetylthio)methyl]-1-oxo-3-phenylpropyl]-, phenylmethyl ester
- SMR000449320
- SR-01000759384
- Racecadotril [INN:BAN]
- UNII-76K53XP4TO
- (+/-)-ACETORPHAN
- benzyl 2-[[(2S)-2-(acetylsulfanylmethyl)-3-phenylpropanoyl]amino]acetate
- 2-[[2-[(acetylthio)methyl]-1-oxo-3-phenylpropyl]amino]acetic acid (phenylmethyl) ester
- 2-{[2-[(acetylthio)methyl]-1-oxo-3-phenylpropyl]amino}acetic acid (phenylmethyl) ester
- Hidrasec (TN)
- Prestwick_926
- Racecadotril-[d5]
- Tiorfan (TN)
- MFCD00865520
- CPD000449320
- Prestwick0_000626
- Prestwick1_000626
- Prestwick2_000626
- Prestwick3_000626
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