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PRADEFOVIR
SynDRA canonical compound SYN0029974 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | CYP3A4 |
|---|
| Mechanism of action | cytochrome P450 activator |
|---|
All known targets
- CYP3A4
- HBV RT
- HSV UL30
- POLG
- P
- HBcAg
Mechanisms of action (all sources)
- cytochrome P450 activator
- HBV RT MODULATOR
- DNA polymerase inhibitor
- HSV UL30 INHIBITOR
- P inhibitor
Drug classes
- Anti-Retroviral Agents
- Antiviral Agents
- Nucleoside Reverse Transcriptase Inhibitors
- Anti-Infective Agents
- Enzyme Inhibitors
- Nucleic Acid Synthesis Inhibitors
- Reverse Transcriptase Inhibitors
- Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
Cross-references
Synonyms
- Remofovir
- Pradefovir mesylate
- Remofovir mesylate
- Hepavir-B
- ICN 2001-3
- MB-06866
- MB-6866
- Pradefovir (oral, hepatitis B), Ligand/Chiva
- GZE85Q9Q61
- MB 06866
- ICN-2001-3
- MB06866
- pradefovirum
- RefChem:175689
- DTXCID401511696
- ICN2001-3
- Pradefovir [INN]
- UNII-GZE85Q9Q61
- PRADEFOVIR [WHO-DD]
- SCHEMBL13680396
- SCHEMBL29366536
- SCHEMBL29467019
- EX-A1920
- AC-35861
- HY-112690
- CS-0062642
- NS00069623
- EX-A1921
- SCHEMBL29711488
- orb1306990
- PRADEFOVIR MESILATE [WHO-DD]
- MB 06866Q
- Pradefovir mesylate (Remofovir mesylate)?
- Pradefovir Mesylate
- RefChem:868367
- Pradefovir mesilate
- Pradefovir mesylate (Remofovir mesylate)
- T19526
Reported adverse events
- Lactic acidosis
- HIV infection
- Lactic acid
- Fanconi syndrome
- Headache
- Asthenia
- Dyspepsia
- Flatulence
- Hepatitis
- Nausea
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