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AZD-7762
SynDRA canonical compound SYN0029338 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | CHEK2 |
|---|
| Mechanism of action | CHK inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- CHK inhibitor
- CHEK1 INHIBITOR
- Serine/threonine-protein kinase Chk1 inhibitor
- CHK1 inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AAK1
- PDGFRB
- MYLK3
- MELK
- MARK4
- MARK3
- MARK2
- MAP4K5
- MAP4K4
- MAP4K3
- MAP4K2
- ABL1
- MAP3K11
- MAP2K5
- MAP2K2
- MAP2K1
- LYN
- LCK
- JAK2
- IRAK4
- HCK
- GAK
- FYN
- FRK
- FES
- FER
- ERN1
- EGFR
- DYRK1A
- PAK4
- PKN1
- CSK
- PKN2
- YES1
- ULK3
- ULK1
- TNK2
- TNIK
- TEC
- SYK
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ABCB5
- HLAB
- IFNB1
- IFNG
- MDR1
- MITF
- NSD2
- PARP1
- TFE3
- TP53
Cross-references
Synonyms
- AZD7762
- AZD 7762
- (S)-5-(3-Fluorophenyl)-N-(piperidin-3-yl)-3-ureidothiophene-2-carboxamide
- UNII-5D822Y3L1H
- 3-(Carbamoylamino)-5-(3-Fluorophenyl)-N-[(3s)-Piperidin-3-Yl]thiophene-2-Carboxamide
- CHEMBL2041933
- 5D822Y3L1H
- J-502468
- 5-(3-Fluorophenyl)-N-[(3s)-3-Piperidyl]-3-Ureido-Thiophene-2-Carboxamide
- IAYGCINLNONXHY-LBPRGKRZSA-N
- YDJ
- AZD7762 hydrochloride
- 5-(3-Fluorophenyl)-3-ureidothiophene-N-[(S)-piperidin-3-yl]-2-carboxamide
- SCHEMBL1127614
- GTPL7713
- AOB1915
- QCR-261
- CHEBI:131156
- 860352-01-8 (free base)
- 2-Thiophenecarboxamide, 3-((aminocarbonyl)amino)-5-(3-fluorophenyl)-N-(3S)-3-piperidinyl-
- AZD 7762 [WHO-DD]
- BCPP000366
- DTXSID001025611
- EX-A1548
- WZB09478
- BDBM50389803
- NSC757148
- NSC799350
- s1532
- ZINC33359230
- AKOS005266646
- BCP9000356
- CCG-264907
- CS-0025
- DB12242
- NSC-757148
- NSC-799350
- NCGC00242481-01
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