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PF-4136309
SynDRA canonical compound SYN0029191 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Mechanism of action | CC chemokine receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- CCR2 ANTAGONIST
- C-C chemokine receptor type 2 antagonist
- CC chemokine receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADGRF1
- MUTYH
- GPR119
- GPR35
- HDAC6
- KCNH2
- MBD4
- MPG
- NEIL1
- FPR2
- NEIL2
- NTHL1
- OGG1
- S1PR1
- SMUG1
- TDG
- GLP1R
- FFAR4
- ADRA2A
- CCR5
- ADRB2
- AGTR1
- APLNR
- C5AR1
- CCR1
- CCR3
- CX3CR1
- CYP3A4
- CXCR3
- CXCR5
- CYP1A2
- CYP2C19
- CYP2C9
- CYP2D6
- UNG
Cross-references
Synonyms
- PF-04136309
- INCB-8761
- INCB8761
- PF 4136309
- INCB 8761
- INCB8761(PF-4136309)
- PF4136309
- CHEMBL2029422
- N-[2-[(3S)-3-[[4-hydroxy-4-(5-pyrimidin-2-ylpyridin-2-yl)cyclohexyl]amino]pyrrolidin-1-yl]-2-oxoethyl]-3-(trifluoromethyl)benzamide
- N-[2-((3S)-3-{[4-Hydroxy-4-(5-pyrimidin-2-ylpyridin-2-yl)cyclohexyl]amino}pyrrolidin-1-yl)-2-oxoethyl]-3-(trifluoromethyl)benzamide
- INCB8761 PF-4136309
- INCB8761/PF-4136309
- SCHEMBL1377713
- GTPL9032
- ZNSVOHSYDRPBGI-CBQRAPNFSA-N
- MolPort-039-139-774
- SCHEMBL13613003
- SB17393
- INCB8761 (PF-4136309)
- ZNSVOHSYDRPBGI-UHFFFAOYSA-N
- C29H31F3N6O3
- 3M2595V4KT
- PF-4136309 [WHO-DD]
- NCGC00390572-01
- NSC-796433
- HY-13245
- F986452
- C12852
- GLXC-24274
- EX-A2696
- F601112
- NSC796433
- CS-0610
- GLXC-10083
- BRD-K94420399-001-01-9
- BS-51392
- AS-75226
- (Rac)-PF-4136309
- ZNSVOHSYDRPBGI-LXWOLXCRSA-N
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