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PF-04217903
SynDRA canonical compound SYN0028902 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | MET |
|---|
| Mechanism of action | C-Met inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- MET INHIBITOR
- Hepatocyte growth factor receptor inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AAK1
- PAK4
- PDE2A
- PDE1C
- PDE1A
- PDE11A
- PDE10A
- PCYT1A
- PBK
- PASK
- PAK6
- PAK2
- PDE3B
- PAICS
- OPA1
- OLA1
- OGG1
- NUAK2
- NTRK3
- NTRK2
- NTRK1
- NTHL1
- PDE3A
- PDE4C
- NLK
- PIP4K2C
- PRKACA
- PRKAA1
- PLK4
- PLK3
- PLK1
- PKN3
- PKN2
- PKN1
- PKMYT1
- PIP4K2A
- PDE4D
- PIM2
- PIM1
- PHKG2
Cross-references
Synonyms
- MET TYROSINE KINASE INHIBITOR PF-04217903
- PF-4217903
- 2-(4-(1-(Quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol
- PF 04217903
- PF04217903
- UNII-CYJ9ATV1IJ
- CYJ9ATV1IJ
- CHEMBL2001019
- aka PF-04217903
- C19H16N8O
- 2-[4-(3-Quinolin-6-ylmethyl-3H-[1,2,3]triazolo[4,5-b]pyrazin-5-yl)-pyrazol-1-yl]-ethanol
- 2-(4-(1-(Quinolin-6-ylmethyl)-1H-(1,2,3)triazolo(4,5-b)pyrazin-6-yl)-1H-pyrazol-1-yl)ethanol
- 3zxz
- PDMUGYOXRHVNMO-UHFFFAOYSA-N
- Met tyrosine kinase inhibitor PF-04217903
- RefChem:172228
- DTXCID80881713
- MFCD12407410
- PF-04217903 (phenolsulfonate)
- Kinome_3829
- SCHEMBL93550
- MLS006010959
- orb1305179
- SCHEMBL29355971
- SCHEMBL29394198
- CHEBI:91425
- EX-A478
- GLXC-90210
- HMS3244G11
- HMS3244G12
- HMS3244H11
- HMS3295M07
- HMS3654I19
- BDBM50396934
- NSC763931
- NSC800845
- s1094
- AKOS026750596
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