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AZD-1080
SynDRA canonical compound SYN0028827 — structure-anchored drug synonym record
| Clinical phase | Phase 1 |
|---|
| Primary target(s) | GSK3A | GSK3B |
|---|
| Mechanism of action | glycogen synthase kinase inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- GSK3A INHIBITOR
- Glycogen synthase kinase-3 inhibitor
- GSK3B INHIBITOR
- glycogen synthase kinase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACVR1
- MST1R
- NEK4
- NTRK1
- NTRK2
- NTRK3
- PAK1
- PAK4
- PBK
- PDGFRA
- PDGFRB
- PDPK1
- PHKG2
- PIM1
- PIM2
- PIM3
- PKN2
- NEK2
- MKNK2
- PLK3
- MINK1
- MAP4K5
- MAPK1
- MAPK12
- MAPK13
- MAPK14
- MAPK8
- MAPK9
- MAPKAPK2
- MAPKAPK3
- MAPKAPK5
- MARK2
- MARK3
- MATK
- MELK
- MET
- PLK1
- PLK4
- AKT1
- RPS6KA3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ADCY9
- CP2C9
- CP2D6
- CP3A7
- DYR1B
- KCC2A
- KCC2G
- KPCD2
- ST17A
Cross-references
Synonyms
- AZ-11548415
- AZD1080
- 0TII45R8IJ
- CHEBI:167651
- RefChem:115984
- UNII-0TII45R8IJ
- MFCD12031593
- Kinome_2945
- SCHEMBL394519
- GTPL7819
- orb1307560
- SCHEMBL18642421
- SCHEMBL18642422
- SCHEMBL22604618
- SCHEMBL29361806
- SCHEMBL29374248
- SCHEMBL30298327
- SCHEMBL31032587
- EX-A230
- BLTVBQXJFVRPFK-UHFFFAOYSA-N
- GLXC-90136
- HMS3653I11
- HMS3886F11
- AZD1080?
- MZA48772
- BDBM50267626
- s7145
- AKOS026674123
- AKOS026750189
- AKOS032947292
- CCG-267852
- CS-1520
- NCGC00386283-04
- NCGC00386283-07
- NCGC00389257-01
- AC-32728
- AS-55896
- HY-13862
- DB-293119
Look up AZD-1080 in the interactive SynDRA portal →