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APITOLISIB
SynDRA canonical compound SYN0028399 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | PIK3CG |
|---|
| Mechanism of action | PI3K inhibitor |
|---|
All known targets
- MTOR
- PIK3CG
- PIK3CA
- PIK3CB
- PIK3CD
- FGR
- MAP3K9
- SYK
- PIK3R1
- PIK3R2
- PIK3R3
- PIK3R5
Mechanisms of action (all sources)
- MTOR inhibitor
- PI3K inhibitor
- Serine/threonine-protein kinase mTOR inhibitor
- PIK3R1 INHIBITOR
- PIK3CB INHIBITOR
- PIK3CG INHIBITOR
- PIK3CA INHIBITOR
- PIK3R2 INHIBITOR
- PIK3CD INHIBITOR
- PIK3R5 INHIBITOR
- PIK3R3 INHIBITOR
- FGR INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AAK1
- PGRMC1
- PIK3C3
- PIK3C2B
- PIK3C2A
- PI4KB
- PI4KA
- PHKG2
- PFKP
- PAICS
- PEBP1
- PDXK
- PDGFRB
- PARP1
- PAK6
- PAK4
- PIM1
- PIP4K2A
- PIP4K2C
- PKMYT1
- PKN1
- PKN2
- PLK4
- PRKAA1
- PRKACA
- PRKACB
- PRKACG
- PRKAG1
- PRKAG2
- PRKAR2A
- PRKCA
- PRKCB
- PRKCD
- PAK2
- OPA1
- PRKCQ
- MARK2
- MELK
- MDN1
- MCM4
Cross-references
Synonyms
- GNE-390
- RG-7422
- APITOLISIB (GDC-0980)
- G-038390
- G-038390.1
- GDC-0980
- GDC-0980 (RG7422)
- GDC-0980.1
- GDC-0980/RG7422
- RG7422
- GDC0980
- (S)-1-(4-((2-(2-aminopyrimidin-5-yl)-7-methyl-4-morpholinothieno[3,2-d]pyrimidin-6-yl)methyl)piperazin-1-yl)-2-hydroxypropan-1-one
- UNII-1C854K1MIJ
- Apitolisib (GDC-0980, RG7422)
- 1C854K1MIJ
- CHEMBL1922094
- (2s)-1-(4-{[2-(2-Aminopyrimidin-5-Yl)-7-Methyl-4-(Morpholin-4-Yl)thieno[3,2-D]pyrimidin-6-Yl]methyl}piperazin-1-Yl)-2-Hydroxypropan-1-One
- J-502360
- C23H30N8O3S
- GDC 0980
- Gne-390
- apitolisibum
- RefChem:1077141
- DTXCID1068229
- Apitolisib [USAN:INN]
- GDC-0980 (Apitolisib)
- MFCD20274520
- Apitolisib (GDC-0980)
- GNE 390; GDC 0980; RG 7422
- APITOLISIB [INN]
- Apitolisib (USAN/INN)
- APITOLISIB [USAN]
- APITOLISIB [WHO-DD]
- Apitolisib(GDC-0980)?
- SCHEMBL466297
- GTPL7888
- orb1307117
- SCHEMBL29447291
- EX-A041
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