← SynDRA
AZD1981
SynDRA canonical compound SYN0028390 — structure-anchored drug synonym record
| Clinical phase | Phase 2 |
|---|
| Primary target(s) | PTGDR2 |
|---|
| Mechanism of action | CRTH receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- PTGDR2 ANTAGONIST
- G protein-coupled receptor 44 antagonist
- CRTH receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AKR1B1
- ADGRF1
- HDAC6
- TDG
- TBXA2R
- SMUG1
- S1PR1
- PTGS1
- PTGDR
- OGG1
- NTHL1
- NEIL2
- NEIL1
- MUTYH
- MPG
- MBD4
- GPR35
- ADRA2A
- GPR119
- GLP1R
- FPR2
- FFAR4
- CYP3A4
- CYP2D6
- CYP2C9
- CYP1A2
- CX3CR1
- C5AR1
- APLNR
- AGTR1
- ADRB2
- UNG
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Cross-references
Synonyms
- Azd-1981
- AZD 1981
- UNII-2AD53WQ2CX
- 2AD53WQ2CX
- CHEMBL1914489
- 2-[4-acetamido-3-(4-chlorophenyl)sulfanyl-2-methylindol-1-yl]acetic acid
- 1H-Indole-1-acetic acid, 4-(acetylamino)-3-((4-chlorophenyl)thio)-2-methyl-
- 1H-Indole-1-acetic acid, 4-(acetylamino)-3-[(4-chlorophenyl)thio]-2-methyl-
- JWYIGNODXSRKGP-UHFFFAOYSA-N
- GTPL7680
- SCHEMBL1053662
- EX-A662
- MolPort-035-395-811
- HMS3653A06
- BCP20957
- ZINC73196066
- s7263
- BDBM50357102
- AKOS027263775
- SB16902
- DB11946
- CS-4189
- NCGC00386290-04
- HY-15950
- SC-94603
- AZD-1981
- RefChem:116032
- MFCD26936340
- orb1300801
- SCHEMBL30538014
- AZD 1981 [WHO-DD]
- AZD1981?
- CCG-268510
- AC-33100
- AC-33101
- AS-75220
- DB-099530
- NS00072977
Look up AZD1981 in the interactive SynDRA portal →