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TROSPIUM
SynDRA canonical compound SYN0028028 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CHRM1 |
|---|
| Mechanism of action | acetylcholine receptor antagonist |
|---|
| Indication | urinary frequency | urinary incontinence |
|---|
| Disease area | urology |
|---|
All known targets
- CHRM1
- CHRM2
- CHRM3
- CHRM5
- CHRM4
Mechanisms of action (all sources)
- CHRM3 ANTAGONIST
- CHRM2 ANTAGONIST
- acetylcholine receptor antagonist
- CHRM5 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- OPRK1
- HTR2C
- HTR3A
- KCNH2
- MAOA
- MC3R
- MC4R
- MLNR
- NPY1R
- NR1I2
- NR3C1
- OPRD1
- OPRM1
- ADORA2A
- PDE3A
- PDE4D
- PGR
- PTGS2
- SLC22A3
- SLC29A1
- SLC47A1
- SLC47A2
- SLC6A2
- SLC6A3
- SLC6A4
- HTR2B
- HTR2A
- HTR1A
- HRH3
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
- AVPR2
Drug classes
- Cholinergic Muscarinic Antagonists
- Cholinergic Agents
- Cholinergic Antagonists
- Muscarinic Antagonists
- Neurotransmitter Agents
- Parasympatholytics
- Peripheral Nervous System Agents
- Urological Agents
- Cholinergic Muscarinic Antagonist
ATC classes
- G04B · UROLOGICALS
- ANTISPASMODICS IN COMBINATION WITH ANALGESICS
Cross-references
Synonyms
- COBENFY
- SANCTURA
- SANCTURA XR
- TROSPIUM CHLORIDE
- trospium chloride
- relaspium
- Trospium cation
- Trospium ion
- Spasmex
- Spasmoplex
- Trosec
- Regurin (TN)
- Sanctura (TN)
- Spasmex (TN)
- Spasmoplex (TN)
- Trosec (TN)
- Trospium chloride (JAN/USAN/INN)
- 8-Benziloyloxy-6,10-ethano-5-azoniaspiro(4.5)decane chloride
- Trospium chloride
- Regurin
- Sanctura
- Relaspium
- Cloruro de trospio
- Chlorure de trospium
- Santura
- Spasmo-lyt
- Trospium Cl
- Sanctura XR
- Trospii chloridum
- Spasmo 3
- Uraplex
- IP631
- Trospium (chloride)
- IP-631
- MFCD00865254
- 1E6682427E
- DTXCID903724
- Keptan
Reported adverse events
- Abdominal pain
- Constipation
- Dry mouth
- Dyspepsia
- Flatulence
- Headache
- Stevens-Johnson syndrome
- Urinary retention
- Abdominal pain upper
- Dry eye
- Fatigue
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