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DACTOLISIB
SynDRA canonical compound SYN0027972 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Primary target(s) | PIK3CG |
|---|
| Mechanism of action | PI3K inhibitor |
|---|
All known targets
- MTOR
- PIK3CG
- PIK3CA
- PIK3CD
- ATR
- PIK3CB
- PIK3R1
- PIK3R2
- PIK3R3
- PIK3R5
Mechanisms of action (all sources)
- MTOR inhibitor
- PI3K inhibitor
- Serine/threonine-protein kinase mTOR inhibitor
- PIK3R1 INHIBITOR
- PIK3CB INHIBITOR
- PIK3CG INHIBITOR
- PIK3CA INHIBITOR
- PIK3R2 INHIBITOR
- PIK3CD INHIBITOR
- PIK3R5 INHIBITOR
- PIK3R3 INHIBITOR
- ATR inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- AAK1
- ABCB11
- PGRMC1
- PFKP
- PEBP1
- PDXK
- PDGFRB
- PDGFRA
- PCYT1A
- PAK6
- PAK4
- PAK2
- PAICS
- OPA1
- OLA1
- NUAK2
- NTRK3
- NTRK2
- NTRK1
- PHKG2
- PIK3C2A
- PIK3C2B
- PRKAA1
- PRKCA
- PRKAR2A
- PRKAG2
- PRKAG1
- PRKACG
- PRKACB
- PRKACA
- PLK4
- PIK3C3
- PKN3
- PKN2
- PKN1
- PKMYT1
- PIP4K2C
- PIP4K2A
- PIM1
- NQO2
Cross-references
Synonyms
- BEZ-235
- Nvp-bez-235
- RTB101
- BEZ235
- NSC-751249
- NVP-BEZ235
- NVP-BEZ235-NX
- RTB-101
- S14-0511
- NVP-BEZ-235
- NVP-BEZ235, BEZ235
- 2-(4-(2,3-dihydro-3-methyl-2-oxo-8-(quinolin-3-yl)imidazo[4,5-c]quinolin-1-yl)phenyl)-2-methylpropanenitrile
- NVP BEZ235
- NVP BEZ 235
- BEZ 235
- NVPBEZ235
- RUJ6Z9Y0DT
- NSC 751249
- CHEBI:71952
- dactolisibum
- RefChem:585151
- DTXCID10161090
- BEZ235 (NVP-BEZ235, Dactolisib)
- MFCD10565944
- S1009
- BEZ235 (NVP-BEZ235)
- Dactolisib [USAN]
- C30H23N5O
- Dactolisib (BEZ235)
- Dactolisib [USAN:INN]
- UNII-RUJ6Z9Y0DT
- Kinome_2911
- CT-BEZ
- DACTOLISIB [INN]
- Dactolisib (USAN/INN)
- Nvp-bez235, free base
- mTOR Inhibitor, BEZ235
- DACTOLISIB [WHO-DD]
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